Document Detail


Inhibition of pancreatic lipase by phenolic acids--examination in vitro.
MedLine Citation:
PMID:  9031529     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The influence of addition 2,4,6,8, and 10 microM of benzoic and cinnamic acids and selected phenolic acids (salicylic, p-hydroxybenzoic, gentisic, protocatechuic, vanillic, syringic, o-coumaric, p-coumaric, caffeic, ferulic, sinapic) on the activity of pancreatic lipase was examined in vitro. The strongest inhibition activities were observed with caffeic, ferulic and benzoic acid, while sinapic and gentisic acids produced the lowest inhibition.
Authors:
M Karamać; R Amarowicz
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Zeitschrift für Naturforschung. C, Journal of biosciences     Volume:  51     ISSN:  0939-5075     ISO Abbreviation:  Z. Naturforsch., C, J. Biosci.     Publication Date:    1996 Nov-Dec
Date Detail:
Created Date:  1997-04-01     Completed Date:  1997-04-01     Revised Date:  2009-11-04    
Medline Journal Info:
Nlm Unique ID:  8912155     Medline TA:  Z Naturforsch C     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  903-5     Citation Subset:  IM    
Affiliation:
Division of Food Science, Polish Academy of Sciences, Olsztyn, Poland.
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MeSH Terms
Descriptor/Qualifier:
Animals
Caffeic Acids / pharmacology
Cinnamates / pharmacology*
Coumaric Acids / pharmacology*
Hydroxybenzoic Acids / pharmacology*
Lipase / antagonists & inhibitors*
Pancreas / enzymology
Structure-Activity Relationship
Chemical
Reg. No./Substance:
0/Caffeic Acids; 0/Cinnamates; 0/Coumaric Acids; 0/Hydroxybenzoic Acids; 331-39-5/caffeic acid; EC 3.1.1.3/Lipase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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