Document Detail

Inhibition of pancreatic lipase by phenolic acids--examination in vitro.
MedLine Citation:
PMID:  9031529     Owner:  NLM     Status:  MEDLINE    
The influence of addition 2,4,6,8, and 10 microM of benzoic and cinnamic acids and selected phenolic acids (salicylic, p-hydroxybenzoic, gentisic, protocatechuic, vanillic, syringic, o-coumaric, p-coumaric, caffeic, ferulic, sinapic) on the activity of pancreatic lipase was examined in vitro. The strongest inhibition activities were observed with caffeic, ferulic and benzoic acid, while sinapic and gentisic acids produced the lowest inhibition.
M Karamać; R Amarowicz
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Zeitschrift für Naturforschung. C, Journal of biosciences     Volume:  51     ISSN:  0939-5075     ISO Abbreviation:  Z. Naturforsch., C, J. Biosci.     Publication Date:    1996 Nov-Dec
Date Detail:
Created Date:  1997-04-01     Completed Date:  1997-04-01     Revised Date:  2009-11-04    
Medline Journal Info:
Nlm Unique ID:  8912155     Medline TA:  Z Naturforsch C     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  903-5     Citation Subset:  IM    
Division of Food Science, Polish Academy of Sciences, Olsztyn, Poland.
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MeSH Terms
Caffeic Acids / pharmacology
Cinnamates / pharmacology*
Coumaric Acids / pharmacology*
Hydroxybenzoic Acids / pharmacology*
Lipase / antagonists & inhibitors*
Pancreas / enzymology
Structure-Activity Relationship
Reg. No./Substance:
0/Caffeic Acids; 0/Cinnamates; 0/Coumaric Acids; 0/Hydroxybenzoic Acids; 331-39-5/caffeic acid; EC

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