Document Detail


Inhibition in schizophrenia: association with auditory hallucinations.
MedLine Citation:
PMID:  12837525     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The study investigated whether auditory hallucinations (AH) in schizophrenia are linked to a deficit in inhibition. Two tasks assessing the intentional suppression of cognitive events-the Hayling Sentence Completion Test (HSCT) [Neuropsychologia 34 (1996) 263] and the Inhibition of Currently Irrelevant Memories Task (ICIM) [Nature Neuroscience 2 (1999) 677]-were administered to 42 patients with schizophrenia and 24 normal controls. Presence and severity of symptoms in the patient group were examined using the Positive and Negative Syndrome Scale (PANSS). Patients performed significantly worse on the measures of inhibition compared to controls. More importantly, among patients, significant positive correlations were obtained between an index of AH severity (defined as an increase in frequency of AH on PANSS) and the number of type A errors on the HSCT and errors in the last three runs of the ICIM. An increase in AH severity was, therefore, associated with increasingly impaired control of intentional inhibition. Furthermore, no significant correlations were found between these indices of inhibition and either negative, general or positive symptoms (excluding AH scores).
Authors:
Flavie A V Waters; Johanna C Badcock; Murray T Maybery; Patricia T Michie
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Schizophrenia research     Volume:  62     ISSN:  0920-9964     ISO Abbreviation:  Schizophr. Res.     Publication Date:  2003 Aug 
Date Detail:
Created Date:  2003-07-02     Completed Date:  2003-12-01     Revised Date:  2010-09-02    
Medline Journal Info:
Nlm Unique ID:  8804207     Medline TA:  Schizophr Res     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  275-80     Citation Subset:  IM    
Affiliation:
School of Psychology, University of Western Australia, 35 Stirling Highway, Western Australia 6009, Crawley, Australia. flavie@psy.uwa.edu.au
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MeSH Terms
Descriptor/Qualifier:
Adult
Female
Functional Laterality
Hallucinations / diagnosis,  etiology*
Humans
Inhibition (Psychology)*
Male
Psychological Tests
Schizophrenia / complications*,  diagnosis
Severity of Illness Index

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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