| Inhibition in schizophrenia: association with auditory hallucinations. | |
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MedLine Citation:
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PMID: 12837525 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The study investigated whether auditory hallucinations (AH) in schizophrenia are linked to a deficit in inhibition. Two tasks assessing the intentional suppression of cognitive events-the Hayling Sentence Completion Test (HSCT) [Neuropsychologia 34 (1996) 263] and the Inhibition of Currently Irrelevant Memories Task (ICIM) [Nature Neuroscience 2 (1999) 677]-were administered to 42 patients with schizophrenia and 24 normal controls. Presence and severity of symptoms in the patient group were examined using the Positive and Negative Syndrome Scale (PANSS). Patients performed significantly worse on the measures of inhibition compared to controls. More importantly, among patients, significant positive correlations were obtained between an index of AH severity (defined as an increase in frequency of AH on PANSS) and the number of type A errors on the HSCT and errors in the last three runs of the ICIM. An increase in AH severity was, therefore, associated with increasingly impaired control of intentional inhibition. Furthermore, no significant correlations were found between these indices of inhibition and either negative, general or positive symptoms (excluding AH scores). |
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Authors:
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Flavie A V Waters; Johanna C Badcock; Murray T Maybery; Patricia T Michie |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Schizophrenia research Volume: 62 ISSN: 0920-9964 ISO Abbreviation: Schizophr. Res. Publication Date: 2003 Aug |
Date Detail:
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Created Date: 2003-07-02 Completed Date: 2003-12-01 Revised Date: 2010-09-02 |
Medline Journal Info:
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Nlm Unique ID: 8804207 Medline TA: Schizophr Res Country: Netherlands |
Other Details:
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Languages: eng Pagination: 275-80 Citation Subset: IM |
Affiliation:
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School of Psychology, University of Western Australia, 35 Stirling Highway, Western Australia 6009, Crawley, Australia. flavie@psy.uwa.edu.au |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Female Functional Laterality Hallucinations / diagnosis, etiology* Humans Inhibition (Psychology)* Male Psychological Tests Schizophrenia / complications*, diagnosis Severity of Illness Index |
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