Document Detail

Inhibition of apple 1-aminocyclopropane-1-carboxylic acid oxidase, by cyclopropane-1,1-dicarboxylic acid and trans-2-phenylcyclopropane-1-carboxylic acid.
MedLine Citation:
PMID:  11117889     Owner:  NLM     Status:  Publisher    
Cyclopropane-1,1-dicarboxylic acid (CDA) and trans-2-phenylcyclopropane-1-carboxylic acid (PCCA) are the main representatives of a group of compounds that are structural analogues of 1-aminocyclopropane-1-carboxylic acid (ACC) and have been proved to have an inhibitory effect on the wound ethylene produced by Lycopersicum esculentum fruit discs. During the experiments, that were carried out in this work the inhibition pattern of PCCA and CDA were studied when tested on partially purified apple ACO and their Ki values were determined. A mechanistic proposal was given, in order to explain the kinetic behaviour of the inhibitors. The common feature of these molecules is their cyclopropane ring, with different substitutes mainly at the positions C1 and C2. Two other compounds with similar structure where also tested as inhibitors, in order to clarify the relationship between structure and activity. These compounds are: 2-methyl cyclopropanecarboxylic acid (MCA), and cyclopropanecarboxylic acid (CCA).
Dourtoglou; Koussissi
Related Documents :
17683369 - Structure-activity and high-content imaging analyses of novel tubulysins.
6546949 - Methotrexate analogues. 19. replacement of the glutamate side chain in classical antifo...
321779 - P-aminobenzoic acid derivatives. mode of action and structure-activity relationships in...
20370709 - The peptidomimetic, 1-adamantyl-substituted, and flex-het classes of retinoid-derived m...
12517439 - Synthesis and structure-activity relationships of 5,6,7,8-tetrahydropyrido[3,4-b]pyrazi...
12769 - Synthetic analgesics: n-(1-[2-arylethyl]-4-substituted 4-piperidinyl) n-arylalkanamides.
6885249 - Synthesis of 2-methyl and 2-carboxymethyl derivatives of ornithine and arginine.
15294819 - Overexpression of lactobacillus casei d-hydroxyisocaproic acid dehydrogenase in cheddar...
903709 - Effect of ethynylestradiol on biliary excretion of bile acids, phosphatidylcolines, and...
Publication Detail:
Journal Detail:
Title:  Phytochemistry     Volume:  55     ISSN:  1873-3700     ISO Abbreviation:  Phytochemistry     Publication Date:  2000 Oct 
Date Detail:
Created Date:  2000-12-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0151434     Medline TA:  Phytochemistry     Country:  United States    
Other Details:
Languages:  Eng     Pagination:  203-11     Citation Subset:  -    
Vioryl S.A. Chemical and Agricultural Industry, Kifissia, Athens, Greece.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  A 37-kDa peroxidase secreted from liverworts in response to chemical stress.
Next Document:  An aphid repellent glycoside from Solanum laxum.