Document Detail

Inhibition of acetylcholinesterase activity in the terrestrial isopod Porcellio scaber as a biomarker of organophosphorus compounds in food.
MedLine Citation:
PMID:  14677365     Owner:  NLM     Status:  MEDLINE    
This paper describes the toxicity of organophosphorus pesticide diazinon in juvenile and adult terrestrial isopods Porcellio scaber (Isopoda, Crustacea). The woodlice were exposed to different concentrations of diazinon added to food (5, 10, 50, and 100 or 150 micrograms/g dry food). Weight change and food assimilation efficiency were determined two and four weeks after the exposure. The activity of acetylcholinesterase (AChE) in surviving animals was measured at the end of the experiment. The results show that woodlice exposed to diazinon do not significantly differ from controls in growth and feeding rate. The reduction of AChE activity was observed at the lowest diazinon exposure (5 and 10 micrograms/g dry food). These results suggest that AChE activity might prove a useful biomarker, indicating low levels of organophosphates in food.
Katja Stanek; Elizabeta Gabrijelcic; Damjana Drobne; Polonca Trebse
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Arhiv za higijenu rada i toksikologiju     Volume:  54     ISSN:  0004-1254     ISO Abbreviation:  Arh Hig Rada Toksikol     Publication Date:  2003 Sep 
Date Detail:
Created Date:  2003-12-17     Completed Date:  2004-01-22     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0373100     Medline TA:  Arh Hig Rada Toksikol     Country:  Croatia    
Other Details:
Languages:  eng     Pagination:  183-8     Citation Subset:  IM    
Nova Gorica Polytechnic, Nova Gorica, Slovenia.
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MeSH Terms
Acetylcholinesterase / metabolism*
Cholinesterase Inhibitors / toxicity*
Diazinon / toxicity*
Food Contamination*
Insecticides / toxicity*
Isopoda / drug effects,  enzymology*
Reg. No./Substance:
0/Cholinesterase Inhibitors; 0/Insecticides; 333-41-5/Diazinon; EC

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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