| Inhibition of Fusarium graminearum growth and development by farnesol. | |
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MedLine Citation:
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PMID: 18201191 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The isoprenoid farnesol was previously shown to induce morphological features characteristic of apoptosis in the filamentous fungus Aspergillus nidulans. This study demonstrates that under similar liquid media growth conditions, farnesol also triggers apoptosis in the plant pathogenic fungus Fusarium graminearum. However, unlike A. nidulans, F. graminearum spores treated with farnesol exhibited altered germination patterns and most (>60%) lysed upon prolonged exposure. Given the economic importance of F. graminearum as a pathogen of small grains, this study proposes that farnesol may have potential value as an antifungal compound. |
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Authors:
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Camile P Semighini; Nicholas Murray; Steven D Harris |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2008-01-14 |
Journal Detail:
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Title: FEMS microbiology letters Volume: 279 ISSN: 0378-1097 ISO Abbreviation: FEMS Microbiol. Lett. Publication Date: 2008 Feb |
Date Detail:
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Created Date: 2008-01-25 Completed Date: 2008-04-03 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7705721 Medline TA: FEMS Microbiol Lett Country: England |
Other Details:
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Languages: eng Pagination: 259-64 Citation Subset: IM |
Affiliation:
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Plant Science Initiative and Department of Plant Pathology, University of Nebraska-Lincoln, Lincoln, NE 68588, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Antifungal Agents
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pharmacology* Apoptosis / drug effects Farnesol / pharmacology* Fusarium / drug effects*, growth & development* Spores, Fungal / drug effects |
| Chemical | |
Reg. No./Substance:
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0/Antifungal Agents; 4602-84-0/Farnesol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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