| Inhibin is released together with testosterone by the human testis. | |
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MedLine Citation:
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PMID: 2298866 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The secretion of inhibin by the testis into the circulation was studied by measuring immunoreactive inhibin concentrations in spermatic vein blood samples drawn at 15 min intervals for 4 h. Mean spermatic vein inhibin levels were four times the levels in peripheral blood whereas spermatic vein testosterone (T) levels were 60-fold increased. Inhibin was released in well-defined pulses which coincided with episodes ot T release; both the duration and relative amplitude of inhibin and T pulses were similar. Inhibin pulses were undetectable in peripheral blood. These data suggest that the mechanism responsible for releasing T from the testis also stimulates inhibin release. This mechanism appears to involve LH and Leydig cells. |
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Authors:
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S J Winters |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: The Journal of clinical endocrinology and metabolism Volume: 70 ISSN: 0021-972X ISO Abbreviation: J. Clin. Endocrinol. Metab. Publication Date: 1990 Feb |
Date Detail:
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Created Date: 1990-03-07 Completed Date: 1990-03-07 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0375362 Medline TA: J Clin Endocrinol Metab Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 548-50 Citation Subset: AIM; IM |
Affiliation:
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Department of Medicine, Montefiore Hospital, Pittsburgh, PA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Humans Inhibins / blood*, secretion Leydig Cells / physiology Luteinizing Hormone / physiology Male Oligospermia / blood Testis / blood supply*, physiology Testosterone / blood |
| Grant Support | |
ID/Acronym/Agency:
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HD-19546/HD/NICHD NIH HHS |
| Chemical | |
Reg. No./Substance:
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57285-09-3/Inhibins; 58-22-0/Testosterone; 9002-67-9/Luteinizing Hormone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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