| Inherited dyslipidaemic disorders contributing to coronary heart disease. | |
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MedLine Citation:
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PMID: 19999214 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Lipoprotein (a) [Lp (a)] is an established independent risk factor for premature myocardial infarction (MI)/coronary artery disease (CAD). The study was conducted to determine the value of Lp (a) in prediction of CAD or MI in the offspring at risk. METHODS: A total of 160 subjects were investigated. Serum Lp (a) was measured by ELISA, serum total cholesterol, triglycerides (TG) and HDL-Cholesterol by enzymatic colorimetric methods using standard kits. RESULTS: Differences in levels of total Lp (a) and cholesterol were observed between patients and controls. Both Lp (a) (16.23 +/-1.95 mg/dL) and cholesterol (175.00 +/- 7.60 mg/dL) of group A (patients) were higher than the corresponding controls. However an opposite trend in results was noted for serum HDL-Cholesterol in patients vs. controls. CONCLUSION: Persons found to have elevated levels of Lp (a) should focus on controlling the known modifiable risk factor for heart disease, especially smoking, hypercholesterolemia, obesity, hypertension and sedentary life style. |
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Authors:
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Salma Attaullah; Rahim Bangash; Amanullah; Zahoor Ahmed; Jamilur Rehman |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of Ayub Medical College, Abbottabad : JAMC Volume: 20 ISSN: 1025-9589 ISO Abbreviation: J Ayub Med Coll Abbottabad Publication Date: 2008 Oct-Dec |
Date Detail:
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Created Date: 2009-12-11 Completed Date: 2010-01-15 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8910750 Medline TA: J Ayub Med Coll Abbottabad Country: Pakistan |
Other Details:
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Languages: eng Pagination: 90-3 Citation Subset: IM |
Affiliation:
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Department of Chemical Pathology, Hayatabad Medical Complex, Peshawar, Pakistan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Case-Control Studies Cholesterol / blood, genetics Coronary Artery Disease / blood, genetics* Dyslipidemias / blood, genetics* Female Genetic Predisposition to Disease* Humans Lipoprotein(a) / blood, genetics Male Middle Aged Pedigree |
| Chemical | |
Reg. No./Substance:
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0/Lipoprotein(a); 57-88-5/Cholesterol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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