Document Detail

Inheritance of litter size at birth in farmed arctic foxes (Alopex lagopus, Canidae, Carnivora).
MedLine Citation:
PMID:  17006530     Owner:  NLM     Status:  MEDLINE    
Natural populations of the arctic fox (Alopex lagopus, Canidae, Carnivora) differ drastically in their reproductive strategy. Coastal foxes, which depend on stable food resources, produce litters of moderate size. Inland foxes feed on small rodents, whose populations are characterized by cycling fluctuation. In the years with low food supply, inland fox populations have a very low rate of reproduction. In the years with high food supply, they undergo a population explosion. To gain insight into the genetic basis of the reproductive strategy of this species, we performed complex segregation analysis of the litter size in the extended pedigree of the farmed arctic foxes involving 20,665 interrelated animals. Complex segregation analysis was performed using a mixed model assuming that the trait was under control of a major gene and a large number of additive genetic and random factors. To check the significance of any major gene effect, we used Elston-Stewart transmission probability test. Our analysis demonstrated that the inheritance of this trait can be described within the frameworks of a major gene model with recessive control of low litter size. This model was also supported by the pattern of its familial segregation and by comparison of the distributions observed in the population and that expected under our model. We suggest that a system of balanced polymorphism for litter size in the farmed population might have been established in natural populations of arctic foxes as a result of adaptation to the drastic fluctuations in prey availability.
T I Axenovich; I V Zorkoltseva; I R Akberdin; S V Beketov; S N Kashtanov; I A Zakharov; P M Borodin
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2006-09-27
Journal Detail:
Title:  Heredity     Volume:  98     ISSN:  0018-067X     ISO Abbreviation:  Heredity     Publication Date:  2007 Feb 
Date Detail:
Created Date:  2007-01-26     Completed Date:  2007-04-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0373007     Medline TA:  Heredity     Country:  England    
Other Details:
Languages:  eng     Pagination:  99-105     Citation Subset:  IM    
Department of Genetic Recombination and Segregation, Institute of Cytology and Genetics, Siberian Department of Russian Academy of Science, Novosibirsk, Russia.
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MeSH Terms
Animals, Domestic
Foxes / genetics*
Gene Frequency
Inheritance Patterns*
Litter Size / genetics*
Models, Genetic
Polymorphism, Genetic
Quantitative Trait Loci
Comment In:
Heredity. 2007 Feb;98(2):63-4   [PMID:  17180165 ]

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