Document Detail

Inheritance of blood pressure and haemodynamic phenotypes measured at rest and during supine dynamic exercise.
MedLine Citation:
PMID:  1653802     Owner:  NLM     Status:  MEDLINE    
Thirty-two pairs of monozygotic and 21 pairs of dizygotic male twins aged between 18 and 31 years were studied. Blood pressure was measured and Doppler echocardiography at the level of the aorta was performed in resting conditions and at two levels of supine submaximal bicycle exercise (at a fixed work load of 60 W and at a work load corresponding to a heart rate of 110 beats/min). In resting conditions, a genetic component in the variability of systolic and diastolic blood pressure was found; during submaximal supine exercise only a minor genetic effect was observed. At rest, genetic variance was shown for left ventricular outflow haemodynamics and for peripheral vascular resistance. However, during exercise, the transmissible effect on haemodynamics and peripheral resistance was small.
E C Bielen; R H Fagard; A K Amery
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of hypertension     Volume:  9     ISSN:  0263-6352     ISO Abbreviation:  J. Hypertens.     Publication Date:  1991 Jul 
Date Detail:
Created Date:  1991-10-17     Completed Date:  1991-10-17     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  8306882     Medline TA:  J Hypertens     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  655-63     Citation Subset:  IM    
Department of Pathophysiology, Faculty of Medicine, Catholic University of Leuven, Belgium.
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MeSH Terms
Aorta / anatomy & histology
Blood Pressure / genetics*
Echocardiography, Doppler
Heart Atria / anatomy & histology
Hemodynamics / genetics*
Physical Exertion / physiology*
Reference Values
Regression Analysis
Reproducibility of Results
Supination / physiology
Twins, Dizygotic / genetics*
Twins, Monozygotic / genetics*
Vascular Resistance / physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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