Document Detail


Inhaled steroids: effect on intraocular pressure in patients without glaucoma.
MedLine Citation:
PMID:  8743219     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To evaluate the risk of intraocular pressure (IOP) elevation in patients receiving inhaled steroid therapy. DESIGN: Prospective study. SETTING: Four private practices in New Jersey. PATIENTS: A total of 187 patients (99 men and 88 women) with no documented history of glaucoma about to begin inhaled steroid therapy for various pulmonary conditions were enrolled. Of the 187, 183 were followed at 12 weeks. INTERVENTIONS: Measurement of the IOP with the Tono-Pen before therapy was started and 12 weeks after therapy was started. OUTCOME MEASURE: IOP. RESULTS: No significant rise in IOP was observed. No patient had a rise in IOP greater than 4 mm Hg. CONCLUSIONS: Although isolated case reports indicate a definite risk of glaucoma in the presence of inhaled steroid therapy, the risk appears to be small.
Authors:
N Samiy; D S Walton; E B Dreyer
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Canadian journal of ophthalmology. Journal canadien d'ophtalmologie     Volume:  31     ISSN:  0008-4182     ISO Abbreviation:  Can. J. Ophthalmol.     Publication Date:  1996 Apr 
Date Detail:
Created Date:  1996-12-11     Completed Date:  1996-12-11     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0045312     Medline TA:  Can J Ophthalmol     Country:  CANADA    
Other Details:
Languages:  eng     Pagination:  120-3     Citation Subset:  IM    
Affiliation:
Glaucoma Consultation Service, Massachusetts Eye and Ear Infirmary, Boston 02114, USA.
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MeSH Terms
Descriptor/Qualifier:
Administration, Inhalation
Adult
Aged
Female
Glaucoma / physiopathology*
Humans
Intraocular Pressure / drug effects*
Male
Middle Aged
Reference Values
Steroids / administration & dosage*,  adverse effects*,  therapeutic use
Grant Support
ID/Acronym/Agency:
R01-EY 10009/EY/NEI NIH HHS
Chemical
Reg. No./Substance:
0/Steroids

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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