Document Detail

Inhaled steroids: effect on intraocular pressure in patients without glaucoma.
MedLine Citation:
PMID:  8743219     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To evaluate the risk of intraocular pressure (IOP) elevation in patients receiving inhaled steroid therapy. DESIGN: Prospective study. SETTING: Four private practices in New Jersey. PATIENTS: A total of 187 patients (99 men and 88 women) with no documented history of glaucoma about to begin inhaled steroid therapy for various pulmonary conditions were enrolled. Of the 187, 183 were followed at 12 weeks. INTERVENTIONS: Measurement of the IOP with the Tono-Pen before therapy was started and 12 weeks after therapy was started. OUTCOME MEASURE: IOP. RESULTS: No significant rise in IOP was observed. No patient had a rise in IOP greater than 4 mm Hg. CONCLUSIONS: Although isolated case reports indicate a definite risk of glaucoma in the presence of inhaled steroid therapy, the risk appears to be small.
N Samiy; D S Walton; E B Dreyer
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Canadian journal of ophthalmology. Journal canadien d'ophtalmologie     Volume:  31     ISSN:  0008-4182     ISO Abbreviation:  Can. J. Ophthalmol.     Publication Date:  1996 Apr 
Date Detail:
Created Date:  1996-12-11     Completed Date:  1996-12-11     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0045312     Medline TA:  Can J Ophthalmol     Country:  CANADA    
Other Details:
Languages:  eng     Pagination:  120-3     Citation Subset:  IM    
Glaucoma Consultation Service, Massachusetts Eye and Ear Infirmary, Boston 02114, USA.
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MeSH Terms
Administration, Inhalation
Glaucoma / physiopathology*
Intraocular Pressure / drug effects*
Middle Aged
Reference Values
Steroids / administration & dosage*,  adverse effects*,  therapeutic use
Grant Support
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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