| Inhaled Iloprost as a Rescue Therapy for Transposition of the Great Arteries With Persistent Pulmonary Hypertension of the Newborn. | |
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MedLine Citation:
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PMID: 23143352 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Transposition of the great arteries (TGA) in the newborn combined with persistent pulmonary hypertension was reported previously to occur in 3-12 % of full-term neonates with TGA. Right-to-left shunting at the ductal level causes severe hypoxemia despite prostaglandin infusion and balloon atrial septostomy. Although the introduction of inhaled nitric oxide (iNO) has improved the prognosis, this condition still is associated with high preoperative mortality. This report describes the case of a newborn with TGA and persistent pulmonary hypertension, which was managed successfully with oral sildenafil, iNO, and inhaled iloprost during life-threatening acute pulmonary hypertension, thus preventing the use of extracorporeal membrane oxygenation. |
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Authors:
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Alejandro Avila-Alvarez; Maria Carmen Bravo-Laguna; Lucía Deiros Bronte; Maria Jesus Del Cerro |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-11-11 |
Journal Detail:
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Title: Pediatric cardiology Volume: - ISSN: 1432-1971 ISO Abbreviation: Pediatr Cardiol Publication Date: 2012 Nov |
Date Detail:
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Created Date: 2012-11-12 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8003849 Medline TA: Pediatr Cardiol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Neonatal Intensive Care Unit, Department of Neonatology, Hospital Infantil Universitario La Paz, Paseo de la Castellana, 261, 28046, Madrid, Spain, alexavila81@hotmail.com. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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