Document Detail

Inhalative occupational and ingestive immediate-type allergy caused by chicory (Cichorium intybus).
MedLine Citation:
PMID:  8877160     Owner:  NLM     Status:  MEDLINE    
We report a first case of occupational allergy to chicory (Cichorium intybus) in a vegetable wholesaler. Symptoms occurred after oral, cutaneous or inhalatory exposure. The patient also reported reactions after ingestion of botanically related endive (Cichorium endivia) and lettuce (Lactuca sativa). We identified the responsible allergen by SDS-PAGE and immunoblot to be a 48-kDa protein, confined to the non-illuminated parts of the plants. No cross-reactivity was found with mugwort (Artemisia vulgaris), ryegrass (Lolium perenne), and birch (Betula verrucosa) pollen, which suggests that the vegetable is the primary allergenic material.
P Cadot; A M Kochuyt; R Deman; E A Stevens
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology     Volume:  26     ISSN:  0954-7894     ISO Abbreviation:  Clin. Exp. Allergy     Publication Date:  1996 Aug 
Date Detail:
Created Date:  1997-02-04     Completed Date:  1997-02-04     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8906443     Medline TA:  Clin Exp Allergy     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  940-4     Citation Subset:  IM    
Department of Clinical Immunology, University Hospital, Leuven, Belgium.
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MeSH Terms
Administration, Inhalation
Administration, Oral
Chicory / adverse effects*,  immunology
Food Hypersensitivity / etiology*
Hypersensitivity, Immediate / chemically induced*
Occupational Exposure / adverse effects*

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