Document Detail


Inhalation anesthetics: a review.
MedLine Citation:
PMID:  20203550     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Inhalation agents represent a basic drug used in modern balanced anesthesia. In the present review, the pharmacokinetics, effectiveness and clinical effects of inhalation agents on different systems are discussed. Data concerning the metabolism and related toxicity of halogenated agents is reviewed, with particular regard to the problem of chronic exposure to traces of anesthetic gases in the operating room. The cardioprotective effect of halogenated agents and the actual role of nitrous oxide and xenon are discussed. The different mechanisms of action of the inhalation agents and the evolution from a unitary theory of inhaled anesthetics to a multiple mechanism concept are presented.
Authors:
G Torri
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Minerva anestesiologica     Volume:  76     ISSN:  1827-1596     ISO Abbreviation:  Minerva Anestesiol     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-03-05     Completed Date:  2010-05-25     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0375272     Medline TA:  Minerva Anestesiol     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  215-28     Citation Subset:  IM    
Affiliation:
Department of Anesthesiology, S. Raffaele University, Milan, Italy. torri.giorgio@hsr.it
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MeSH Terms
Descriptor/Qualifier:
Anesthesia, Inhalation
Anesthetics, Inhalation / adverse effects,  chemistry,  pharmacokinetics,  pharmacology*
Cardiotonic Agents / pharmacology
Central Nervous System / drug effects
Hemodynamics / drug effects
Humans
Muscle Relaxants, Central
Nitrous Oxide / adverse effects
Respiratory System / drug effects
Chemical
Reg. No./Substance:
0/Anesthetics, Inhalation; 0/Cardiotonic Agents; 0/Muscle Relaxants, Central; 10024-97-2/Nitrous Oxide

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