| Inguinal hernia after radical prostatectomy for prostate cancer: results from a randomized setting and a nonrandomized setting. | |
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MedLine Citation:
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PMID: 20728265 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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BACKGROUND: Observational data indicate that retropubic radical prostatectomy (RRP) for prostate cancer (PCa) may induce inguinal hernia (IH) formation. Little is known about the influence of robot-assisted radical prostatectomy (RALP) on IH risk. OBJECTIVE: To compare the incidence of IH after RRP and RALP to that of nonoperated patients with PCa and to a population control. DESIGN, SETTING, AND PARTICIPANTS: We studied two groups. All 376 men included in the Scandinavian Prostate Cancer Group Study Number 4 constitute study group 1. Patients were randomly assigned RRP or watchful waiting (WW). The 1411 consecutive patients who underwent RRP or RALP at Karolinska University Hospital constitute study group 2. Men without PCa, matched for age and residence to each study group, constitute controls. MEASUREMENTS: Postoperative IH incidence was detected through a validated questionnaire. The participation rates were 82.7% and 88.4% for study groups 1 and 2, respectively. RESULTS AND LIMITATIONS: The Kaplan-Meier cumulative occurrence of IH development after 48 mo in study group 1 was 9.3%, 2.4%, and 0.9% for the RRP, the WW, and the control groups, respectively. There were statistically significant differences between the RRP group and the WW and control groups, but not between the last two. In study group 2 the cumulative risk of IH development at 48 mo was 12.2%, 5.8%, and 2.6% for the RRP, the RALP, and the control group, respectively. There were statistically significant differences between the RRP group and the RALP and control groups, but not between the last two. CONCLUSIONS: RRP for PCa leads to an increased risk of IH development. RALP may lower the risk as compared to open surgery. |
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Authors:
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Johan Stranne; Eva Johansson; Andreas Nilsson; Anna Bill-Axelson; Stefan Carlsson; Lars Holmberg; Jan-Erik Johansson; Tommy Nyberg; Mirja Ruutu; N Peter Wiklund; Gunnar Steineck |
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Publication Detail:
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Type: Journal Article Date: 2010-08-11 |
Journal Detail:
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Title: European urology Volume: 58 ISSN: 1873-7560 ISO Abbreviation: Eur. Urol. Publication Date: 2010 Nov |
Date Detail:
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Created Date: 2011-03-18 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7512719 Medline TA: Eur Urol Country: Switzerland |
Other Details:
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Languages: eng Pagination: 719-26 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 European Association of Urology. Published by Elsevier B.V. All rights reserved. |
Affiliation:
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Department of Oncology and Pathology, Division of Clinical Cancer Epidemiology, Karolinska Institute, Stockholm, Sweden; Department of Urology, Sahlgrenska University Hospital, Gothenburg, Sweden. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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