Document Detail

Infusion thrombophlebitis in a surgical department.
MedLine Citation:
PMID:  411297     Owner:  NLM     Status:  MEDLINE    
In hospitals where 5% glucose is the solution most often infused, the incidence of thrombophlebitis has been found to be 27-43%. In an attempt to reduce this incidence, the following principles for the administration of intravenous solutions were established in a surgical department: (1) No cannula to be placed in the same vein for continuous infusion for a period of more than 24 hours, (2) All sugar solutions to be neutralized with a phosphate buffer. (3) The thinnest possible cannulas are to be used. (4) Vein irritant solutions to be given as quickly as permissible. (5) Veins with the largest diameter to be used first. These principles were adhered to for a period of 4 months. The daily infusion period was 11-14 hours. Of 196 patients who received infusions for a total of 529 days, infusion thrombophlebitis developed in 6.1% (3-10%). 113 of these patients received (among other solutions) 1000-2000 ml 10% invertose per day. This solution was given for an average of 4 days. 9.7% (5-17%) of the patients in this group developed infusion thrombophlebitis. No patient had more than one episode of infusion thrombophlebitis.
I Hessov; J Allen; K Arendt; L Gravholt
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta chirurgica Scandinavica     Volume:  143     ISSN:  0001-5482     ISO Abbreviation:  Acta Chir Scand     Publication Date:  1977  
Date Detail:
Created Date:  1977-12-29     Completed Date:  1977-12-29     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7906530     Medline TA:  Acta Chir Scand     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  151-4     Citation Subset:  IM    
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MeSH Terms
Infusions, Parenteral / adverse effects*
Parenteral Nutrition / adverse effects*
Surgical Procedures, Operative*
Thrombophlebitis / etiology*
Time Factors
Reg. No./Substance:
0/Buffers; 0/Solutions

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