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Information processing limits on generating neuroanatomy: global optimization of rat olfactory cortex and amygdala.
MedLine Citation:
PMID:  19669417     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
A pattern of widespread connection optimization in the nervous system has become evident: deployment of some neural interconnections attains optimality, sometimes without detectable limits. New results for optimization of layout of connected areas of rat olfactory cortex and of rat amygdala are reported here. One larger question concerns mechanisms-how such minimization is attained. A next question is why a nervous system would optimize rather than just moderately satisfice. A morphogenic proposal that relates these questions is that the means of organizing neural wiring happens also to yield optimization. Some neuroanatomy is generated via "saving wire," and this optimizing is via simple physical processes rather than DNA-mediated mechanisms. Such "non-genomic nativism" is thereby a path around fundamental limitations on generating brains, some of the most complex structures in the known universe.
Authors:
Christopher Cherniak; Raul Rodriguez-Esteban
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of biological physics     Volume:  36     ISSN:  1573-0689     ISO Abbreviation:  J Biol Phys     Publication Date:  2010 Jan 
Date Detail:
Created Date:  2009-12-16     Completed Date:  2010-06-09     Revised Date:  2011-07-19    
Medline Journal Info:
Nlm Unique ID:  0417731     Medline TA:  J Biol Phys     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  45-52     Citation Subset:  -    
Affiliation:
Committee for Philosophy and the Sciences, Department of Philosophy, University of Maryland, College Park, MD 20742, USA. cherniak@umd.edu
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