| Influenza-like illness during pregnancy: results from a study in the eastern townships, Province of Quebec. | |
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MedLine Citation:
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PMID: 14663536 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: (1) To assess the frequency of influenza and influenza-like illness (ILI) during pregnancy; (2) to explore the associated risk of adverse maternal and fetal outcomes. METHODS: All women who delivered at the Sherbrooke University Hospital in the province of Quebec during the period of February 15 to April 30, 2002, were invited to complete a questionnaire. Medical records of participating women and of their infants were reviewed. Complement-fixing antibody titres against influenza A were measured in paired sera drawn during antenatal screening and at delivery. RESULTS: The study participation rate was 96.3%. Nine of 517 women stated that they had received the influenza vaccine during pregnancy, and only 3 of 47 women with a chronic pulmonary disease had been immunized. Overall, 464 ILI episodes were reported by 331 women, and a significant maternal complication occurred in 8 cases. ILI episodes resulted in medical consultations in 55.4% of cases, and in antibiotic prescriptions in 13.8% of cases. There was no indication of an increased frequency of adverse perinatal outcomes associated with ILI during pregnancy. Paired sera were available for 156 participants and seroconversion was observed in 6.6%. CONCLUSIONS: ILI during pregnancy was associated with health services utilization but complications were infrequent. More studies are needed to demonstrate the usefulness of routine vaccination of healthy pregnant women against influenza. |
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Authors:
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Jean-de-Dieu Tuyishime; Philippe De Wals; Jean-Marie Moutquin; Eric Frost |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstétrique et gynécologie du Canada : JOGC Volume: 25 ISSN: 1701-2163 ISO Abbreviation: J Obstet Gynaecol Can Publication Date: 2003 Dec |
Date Detail:
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Created Date: 2003-12-09 Completed Date: 2004-02-04 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 101126664 Medline TA: J Obstet Gynaecol Can Country: Canada |
Other Details:
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Languages: eng Pagination: 1020-5 Citation Subset: IM |
Affiliation:
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Clinical Research Centre, Sherbrooke University Hospital Centre, Sherbrooke, Quebec, Canada. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Antibodies, Viral / blood Female Humans Infant, Newborn Influenza A virus / immunology Influenza Vaccines / administration & dosage Influenza, Human / complications, epidemiology*, prevention & control Pregnancy Pregnancy Complications, Infectious / epidemiology* Pregnancy Outcome* / epidemiology Quebec / epidemiology Questionnaires Risk Factors Seroepidemiologic Studies Vaccination |
| Chemical | |
Reg. No./Substance:
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0/Antibodies, Viral; 0/Influenza Vaccines |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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