Document Detail

Influenza-induced rhabdomyolysis after autologous peripheral blood stem cell transplantation for malignant lymphoma.
MedLine Citation:
PMID:  14686755     Owner:  NLM     Status:  MEDLINE    
We report influenza-induced rhabodmyolysis and congestive heart failure after high-dose therapy and hematopoietic stem cell transplantation for malignant lymphoma. Four months after autologous peripheral blood stem cell transplantation for the treatment of malignant lymphoma, a 65-year-old Japanese man developed acute congestive heart failure requiring artificial ventilation and rahbdomyolysis. Since influenza A virus was documented from his nasal cavity, he was diagnosed as rhabdomyolysis and congestive heart failure induced by influenza A infection. Neuraminidase inhibitor (oseltamivir 150 mg/ day for 5 days) was administrated, and heart failure and respiratory status were improved. Our experience suggests that early treatment with neuraminidase inhibitor may improve the clinical outcome of influenza-induced rhabdomyolysis and congestive heart failure.
Masatsugu Nozoe; Tadafumi Iino; Koji Nagafuji; Toshihiro Miyamoto; Hiroyuki Ito; Hisashi Gondo; Mine Harada
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Internal medicine (Tokyo, Japan)     Volume:  42     ISSN:  0918-2918     ISO Abbreviation:  Intern. Med.     Publication Date:  2003 Nov 
Date Detail:
Created Date:  2003-12-22     Completed Date:  2004-04-01     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9204241     Medline TA:  Intern Med     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  1127-30     Citation Subset:  IM    
Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Sciences, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582.
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MeSH Terms
Acetamides / therapeutic use
Antiviral Agents / therapeutic use
Heart Failure / virology*
Hematopoietic Stem Cell Transplantation*
Influenza A virus*
Lymphoma, T-Cell / surgery*
Orthomyxoviridae Infections / drug therapy
Peripheral Blood Stem Cell Transplantation*
Rhabdomyolysis / virology*
Transplantation, Autologous
Reg. No./Substance:
0/Acetamides; 0/Antiviral Agents; 0/Oseltamivir

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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