| Influenza A in immunocompromised patients. | |
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MedLine Citation:
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PMID: 8399875 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Immunocompromised patients with influenza A were identified in Stockholm during two influenza seasons. The predominant subtypes were H3N2 during 1988-1989 and H1N1 during 1990-1991. The median age of the 25 patients was 43 years (range, 3-80 years). Twelve patients had received renal transplants and had ongoing immunosuppression. Seven patients had received bone marrow transplants between 2 days and 3 years before becoming infected with influenza virus A. Two patients were in an aplastic phase, and four had chronic graft-versus-host disease with ongoing immunosuppression. Six patients had hematologic malignancies. Two of the 25 patients had severe infections. One of these infections occurred in a bone marrow transplant recipient during an aplastic phase and was fatal; the other affected a patient who had received a renal transplant. One bone marrow transplant patient had mild but protracted infection. The remaining 22 patients had mild influenza A. We conclude that influenza A in immunocompromised patients occasionally causes severe complications but in most patients is mild and self-limiting. |
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Authors:
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P Ljungman; J Andersson; J Aschan; L Barkholt; A Ehrnst; M Johansson; O Weiland |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America Volume: 17 ISSN: 1058-4838 ISO Abbreviation: Clin. Infect. Dis. Publication Date: 1993 Aug |
Date Detail:
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Created Date: 1993-10-28 Completed Date: 1993-10-28 Revised Date: 2005-11-22 |
Medline Journal Info:
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Nlm Unique ID: 9203213 Medline TA: Clin Infect Dis Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 244-7 Citation Subset: IM |
Affiliation:
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Department of Medicine, Huddinge University Hospital, Karolinska Institute, Sweden. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Aged, 80 and over Bone Marrow Transplantation Child Child, Preschool Female Humans Immunocompromised Host* Immunosuppressive Agents / adverse effects Influenza A virus* Influenza, Human / immunology*, microbiology Kidney Transplantation Middle Aged |
| Chemical | |
Reg. No./Substance:
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0/Immunosuppressive Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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