Document Detail

Influences of stents on the outcome of coil embolized intracranial aneurysms: comparison between a stent-remodeled and non-remodeled treatment.
MedLine Citation:
PMID:  19806305     Owner:  NLM     Status:  MEDLINE    
PURPOSE: The influences of a stent on the outcome of embolized aneurysms are not well known. The purpose of this study is to assess and compare the angiographic follow-up (FU) results of stent-remodeled (StR) and non-remodeled (nonR) coil embolization of intracranial aneurysms. METHODS: Thirty-seven StR patients with FU digital subtraction angiography (DSA) were matched with 37 nonR patients according to presentation (ruptured or unruptured), location of the aneurysm (sidewall or bifurcation), initial sac occlusion (complete/near complete or incomplete/failure), and the sac size (largest diameter/less than 2 mm difference). The baseline clinical and aneurysm characteristics, initial/FU treatment success rates, and FU DSA findings between the StR and nonR groups with regard to the morphologic features (size and location) of the aneurysms were assessed and compared. RESULTS: The StR group showed more frequent progressive thrombosis compared to the nonR group (56.8 vs. 27.0%; p < 0.05). These differences were more prominent for small aneurysms (70 vs. 25%; p < 0.05). Small aneurysms showed a lower rate of FU recanalization in the StR group compared to the nonR group (0 vs. 25%; p < 0.05). Sidewall aneurysms also showed a higher rate of progressive thrombosis in the StR group (61.1 vs. 27.8%; p < 0.05). CONCLUSIONS: Coil embolization is an effective treatment method for intracranial aneurysms, however, changes on follow-up may affect the long-term outcome. Stent remodeling may aid in preserving and enhancing the treatment durability especially in small aneurysms.
Dong Joon Kim; Sang Hyun Suh; Jae Whan Lee; Byung Moon Kim; Jae Wook Lee; Seung Kon Huh; Dong Ik Kim
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't     Date:  2009-10-06
Journal Detail:
Title:  Acta neurochirurgica     Volume:  152     ISSN:  0942-0940     ISO Abbreviation:  Acta Neurochir (Wien)     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-02-26     Completed Date:  2010-06-14     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0151000     Medline TA:  Acta Neurochir (Wien)     Country:  Austria    
Other Details:
Languages:  eng     Pagination:  423-9     Citation Subset:  IM    
Department of Radiology, Research Institute of Radiological Sciences, Yonsei University College of Medicine, Seoul, Korea.
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MeSH Terms
Angiography, Digital Subtraction / methods
Cerebral Arteries / pathology,  physiology,  radiography
Disease Progression
Embolization, Therapeutic / instrumentation*,  methods*
Intracranial Aneurysm / pathology*,  radiography,  therapy*
Intracranial Thrombosis / epidemiology,  pathology,  radiography
Middle Aged
Outcome Assessment (Health Care)
Postoperative Complications / epidemiology,  pathology,  radiography
Prostheses and Implants / standards,  statistics & numerical data
Prosthesis Implantation / methods*
Regeneration / physiology
Severity of Illness Index
Stents / standards,  statistics & numerical data*
Treatment Outcome

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