Document Detail

Influences of laser pulse duration and anastomotic disruption on laser-assisted microvascular anastomoses (LAMA).
MedLine Citation:
PMID:  2355849     Owner:  NLM     Status:  MEDLINE    
The success rate of laser-assisted microvascular anastomosis (LAMA) can be influenced by many factors, including the parameters of the laser technique used. This study examined the effects of laser pulse duration and the occurrence of anastomotic disruption immediately following first repair attempts on the incidence of aneurysm formation and the patency rate in LAMA. Fifty transected rat femoral arteries in 25 rats were anastomosed with three stay sutures and welded with a CO2 laser at a power of 80 mW. In each rat, the laser was applied in the form of 45 pulses of 0.2 sec duration to one femoral artery (group 1) and in the form of 15 pulses of 0.6 sec duration to the contralateral femoral artery (group 2). Comparison of group 1 with group 2 showed that overall rates of aneurysm formation (30% vs. 17%) and patency rates (92% vs. 96%) did not differ significantly (P less than 0.05) at 3 weeks postoperatively. However, disrupted vessels in both groups had a significantly higher incidence of subsequent aneurysm formation than nondisrupted vessels (54% vs. 0% in group 1, P less than 0.05; 43% vs. 6% in group 2, P less than 0.06; groups 1 and 2 pooled, P less than 0.001). These findings indicate that changes in laser pulse duration such as those tested do not affect the aneurysm and patency rates of LAMA. The results demonstrate, however, that disruption after laser welding plays a significant role in subsequent aneurysm formation.
I J Jacobowitz; S Wang; S Basu; F G Baumann; C Marini; J N Cunningham
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Microsurgery     Volume:  11     ISSN:  0738-1085     ISO Abbreviation:  Microsurgery     Publication Date:  1990  
Date Detail:
Created Date:  1990-07-26     Completed Date:  1990-07-26     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8309230     Medline TA:  Microsurgery     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  85-90     Citation Subset:  IM    
Department of Thoracic Surgery, Maimonides Medical Center, Brooklyn, NY 11219.
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MeSH Terms
Anastomosis, Surgical / adverse effects
Aneurysm / etiology*
Femoral Artery / surgery*
Laser Therapy* / adverse effects
Rats, Inbred Strains
Time Factors
Vascular Patency

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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