Document Detail

Influence of water extracts from the surface of two yew (Taxus) species on mites (Tetranychus urticae).
MedLine Citation:
PMID:  11920934     Owner:  NLM     Status:  MEDLINE    
Taxus cuspidata and Taxus media var. Hicksii contain paclitaxel, among other taxoids, on the surface of the needles. These compounds were removed by 5-s dipping of the needles in water just below its boiling point at 96 degrees C and at 60 degrees C and 40 degrees C. Taxus cuspidata contained a fourfold higher concentration of paclitaxel than Taxus media var. Hicksii. The extract with the higher concentration of paclitaxel was more harmful to the mites Tetranychus urticae Koch, increasing their mortality 150%, prolonging development by ca. 20% and lowering the average fecundity from 112 in the control to 16.13 after treatment with Taxus cuspidata; also, the net reproductive rate dropped from 70.24 to 6.70, which is more than a tenfold reduction.
Miroslawa Furmanowa; Danuta Kropczyńska; Alicja Zobel; Kazimierz Glowniak; Hanna Oledzka; Joanna Józefowicz; Agnieszka Sahajdak; Aleksandra Józetczyk
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of applied toxicology : JAT     Volume:  22     ISSN:  0260-437X     ISO Abbreviation:  J Appl Toxicol     Publication Date:    2002 Mar-Apr
Date Detail:
Created Date:  2002-03-28     Completed Date:  2002-08-15     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8109495     Medline TA:  J Appl Toxicol     Country:  England    
Other Details:
Languages:  eng     Pagination:  107-9     Citation Subset:  IM    
Copyright Information:
Copyright 2002 John Wiley & Sons, Ltd.
Department of Biology and Pharmaceutical Botany, Medical University, Banacha Str. 1, 02-097 Warsaw, Poland.
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MeSH Terms
Dose-Response Relationship, Drug
Fertility / drug effects
Longevity / drug effects
Mites / drug effects*
Paclitaxel / isolation & purification,  pharmacology*
Pesticides / pharmacology*
Plant Extracts / chemistry
Taxus / chemistry*
Reg. No./Substance:
0/Pesticides; 0/Plant Extracts; 33069-62-4/Paclitaxel

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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