Document Detail


Influence of vessel size on early and late outcomes after primary angioplasty for acute myocardial infarction.
MedLine Citation:
PMID:  10731257     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Small vessel size is associated with worse outcomes after elective angioplasty, but the effect of vessel size on outcomes after primary angioplasty for acute myocardial infarction has not been studied. We evaluated outcomes in 1,490 consecutive patients treated with primary angioplasty comparing patients with small (< 3.0 mm) versus large ( 3.0 mm) vessels. Outcomes were worse in patients with small vessels with lower procedural success rates (92% versus 96%; p = 0. 002), higher rates of reinfarction (5.5% vs. 3.4%; p = 0.07), more late reocclusion (12.5% vs. 4.1%; p = 0.002), less improvement in ejection fraction (1.8% vs. 4.2%; p = 0.04), lower follow-up ejection fraction (53.7% vs. 56.5%; p = 0.03), and higher 30-day and late mortality (12.5% vs. 6.4%; p = 0.0002). The higher mortality can be explained by a higher baseline risk profile combined with worse procedural results and higher rates of reocclusion and reinfarction. These data stress the importance of developing new strategies to improve procedural and late outcomes after primary angioplasty in patients with small vessels.
Authors:
B R Brodie; T D Stuckey; C Hansen; G Kissling; D Muncy
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  The Journal of invasive cardiology     Volume:  12     ISSN:  1042-3931     ISO Abbreviation:  J Invasive Cardiol     Publication Date:  2000 Jan 
Date Detail:
Created Date:  2000-06-08     Completed Date:  2000-06-08     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8917477     Medline TA:  J Invasive Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  13-9     Citation Subset:  IM    
Affiliation:
520 North Elam Avenue, Greensboro, NC 27403, USA. cvresearch@aol. com.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Angioplasty, Transluminal, Percutaneous Coronary / methods*,  mortality
Chi-Square Distribution
Coronary Angiography
Coronary Vessels / anatomy & histology,  pathology*
Female
Follow-Up Studies
Humans
Logistic Models
Male
Middle Aged
Myocardial Infarction / mortality,  radiography,  therapy*
Myocardial Reperfusion / methods
Proportional Hazards Models
Retrospective Studies
Survival Rate
Time Factors
Comments/Corrections
Comment In:
J Invasive Cardiol. 2000 Jan;12(1):20-2   [PMID:  10731258 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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