Document Detail


Influence of venous congestion on blood-lymph transport of fluid and large molecules in the heat-injured dog's paw.
MedLine Citation:
PMID:  6116837     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Hind paws of anesthetized dogs were exposed to moderate continuous heat (45--52 degrees C). Lymph flow (L) was increased to 5.61 (SD 3.26) times control levels, lymph:plasma concentration ratios for total plasma protein (RT) were increased to 3.23 (SD 1.33), and for exogenous Dextran-110 (RD) to 8.41 (SD 4.00) times control levels. Selectivity of the blood-lymph barrier for individual plasma proteins was also decreased. Elevation of venous pressure during heating resulted in an increase of L in 5 out of 8 experiments, with no consistent change in RT or RD. Increased protein flux was thus closely coupled to increased volume flow. These observations are consistent with the presence and persistence of intercellular openings or gaps in the microvascular endothelium.
Authors:
E M Renkin; C S Sloop; W L Joyner
Related Documents :
7180507 - Effect of histamine and bradykinin on lymph and tissue fluid composition in the rabbit ...
9364197 - Deep cervical lymph flow following the infusion of mannitol in rabbits.
1876597 - The effect of dopamine in a model of biliary acute hemorrhagic pancreatitis.
9220427 - Blood flow patterns in the rat pancreas: a simulative demonstration by injection replic...
6326417 - Unsuitability of blood culture media containing sodium polyanetholesulfonate for the de...
16376767 - Echocardiographic predictors of left atrial appendage spontaneous echocontrast in patie...
Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Lymphology     Volume:  14     ISSN:  0024-7766     ISO Abbreviation:  Lymphology     Publication Date:  1981 Sep 
Date Detail:
Created Date:  1981-12-15     Completed Date:  1981-12-15     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0155112     Medline TA:  Lymphology     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  113-7     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Blood Proteins / analysis*
Dogs
Foot Injuries*
Hindlimb
Hot Temperature / adverse effects*
Hydrostatic Pressure
Lymph / analysis,  physiology*
Saphenous Vein / physiopathology
Veins / physiology*
Grant Support
ID/Acronym/Agency:
HL 10936/HL/NHLBI NIH HHS; HL18010/HL/NHLBI NIH HHS
Chemical
Reg. No./Substance:
0/Blood Proteins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Relative affinities of S 3341 and clonidine for the alpha 2- and alpha 2-adrenoceptors of the rat br...
Next Document:  The treatment of the distal epiphyseal fracture of the tibia (author's transl)