| Influence of venous congestion on blood-lymph transport of fluid and large molecules in the heat-injured dog's paw. | |
| | |
MedLine Citation:
|
PMID: 6116837 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Hind paws of anesthetized dogs were exposed to moderate continuous heat (45--52 degrees C). Lymph flow (L) was increased to 5.61 (SD 3.26) times control levels, lymph:plasma concentration ratios for total plasma protein (RT) were increased to 3.23 (SD 1.33), and for exogenous Dextran-110 (RD) to 8.41 (SD 4.00) times control levels. Selectivity of the blood-lymph barrier for individual plasma proteins was also decreased. Elevation of venous pressure during heating resulted in an increase of L in 5 out of 8 experiments, with no consistent change in RT or RD. Increased protein flux was thus closely coupled to increased volume flow. These observations are consistent with the presence and persistence of intercellular openings or gaps in the microvascular endothelium. |
| | |
Authors:
|
E M Renkin; C S Sloop; W L Joyner |
Related Documents
:
|
11511417 - Hyalomma impeltatum (acari: ixodidae) as a potential vector of malignant theileriosis i... 8326027 - Flow and composition of afferent mammary gland lymph. 20863267 - Lymphatic pump treatment increases thoracic duct lymph flow in conscious dogs with edem... 6716717 - A technique for the perfusion of the isolated rabbit pancreas. 11241707 - Correcting partial volume artifacts of the arterial input function in quantitative cere... 17656667 - Ischemia is not required for arteriogenesis in zebrafish embryos. |
Publication Detail:
|
Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
|
Title: Lymphology Volume: 14 ISSN: 0024-7766 ISO Abbreviation: Lymphology Publication Date: 1981 Sep |
Date Detail:
|
Created Date: 1981-12-15 Completed Date: 1981-12-15 Revised Date: 2008-11-21 |
Medline Journal Info:
|
Nlm Unique ID: 0155112 Medline TA: Lymphology Country: GERMANY, WEST |
Other Details:
|
Languages: eng Pagination: 113-7 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Blood Proteins / analysis* Dogs Foot Injuries* Hindlimb Hot Temperature / adverse effects* Hydrostatic Pressure Lymph / analysis, physiology* Saphenous Vein / physiopathology Veins / physiology* |
| Grant Support | |
ID/Acronym/Agency:
|
HL 10936/HL/NHLBI NIH HHS; HL18010/HL/NHLBI NIH HHS |
| Chemical | |
Reg. No./Substance:
|
0/Blood Proteins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Relative affinities of S 3341 and clonidine for the alpha 2- and alpha 2-adrenoceptors of the rat br...
Next Document: The treatment of the distal epiphyseal fracture of the tibia (author's transl)