| Influence of vagotomy upon GIP release in patients with peptic ulcer. | |
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MedLine Citation:
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PMID: 6385345 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Twenty-two vagotomized peptic ulcer patients were studied on the influence of vagotomy on the release of GIP. Moreover, the relationship between acid output and GIP release was analyzed. These patients underwent one of the three types of operation; truncal vagotomy with pyloroplasty (TV + P) selective vagotomy with pyloroplasty (SV + P) and selective vagotomy with antrectomy (SV + A). Before and after surgery, a gastric juice study and an oral glucose tolerance test were performed on separate days. Maximum acid output in response to tetragastrin correlated significantly with integrated GIP response after oral glucose loading. In the SV + P group, the response of GIP was slightly greater after surgery. In the SV + A group, the integrated GIP response diminished postoperatively, although, after surgery, GIP reached its peak sooner. The integrated GIP response was greater in the SV + P group than in the TV + P group. The response of GIP was less in the SV + A group than in the SV + P group. These changes were insignificant. In conclusion, it is presumed that GIP release is affected by gastric acid, gastric emptying time, intestinal transit time and vagal nerve action. |
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Authors:
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M Imamura; J Kameyama; H Naito; T Sato; A Ohneda |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Tohoku journal of experimental medicine Volume: 143 ISSN: 0040-8727 ISO Abbreviation: Tohoku J. Exp. Med. Publication Date: 1984 Jul |
Date Detail:
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Created Date: 1984-11-20 Completed Date: 1984-11-20 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0417355 Medline TA: Tohoku J Exp Med Country: JAPAN |
Other Details:
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Languages: eng Pagination: 335-44 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Blood Glucose / analysis Female Gastric Acid / secretion Gastric Inhibitory Polypeptide / blood* Gastrointestinal Hormones / blood* Glucose / diagnostic use Humans Insulin / blood Male Middle Aged Peptic Ulcer / metabolism, surgery* Tetragastrin / diagnostic use Vagotomy* Vagotomy, Proximal Gastric |
| Chemical | |
Reg. No./Substance:
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0/Blood Glucose; 0/Gastrointestinal Hormones; 11061-68-0/Insulin; 1947-37-1/Tetragastrin; 50-99-7/Glucose; 59392-49-3/Gastric Inhibitory Polypeptide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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