Document Detail


Influence of sympathectomy on body weight of rats given chow or supermarket diets.
MedLine Citation:
PMID:  4070415     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Rats that were neonatally sympathectomized with guanethidine (GUA) and given access to a four-component supermarket diet (SD) when either adolescent or adult gained weight at the same rate as controls. Adrenodemedullation (MDL) of adults, either alone or in combination with GUA treatment, also failed to influence the development of dietary obesity. Neonatal sympathectomy induced small changes in caloric consumption and diet preferences. These results question the notion that the sympathetic nervous system (SNS) is an essential contributor to the control of body weight and the development of dietary obesity.
Authors:
M G Tordoff
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Physiology & behavior     Volume:  35     ISSN:  0031-9384     ISO Abbreviation:  Physiol. Behav.     Publication Date:  1985 Sep 
Date Detail:
Created Date:  1986-01-22     Completed Date:  1986-01-22     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0151504     Medline TA:  Physiol Behav     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  455-63     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adrenal Medulla / physiology*
Adrenalectomy
Animals
Animals, Newborn
Body Weight*
Diet*
Energy Intake
Feeding Behavior / physiology*
Female
Food Preferences
Guanethidine
Male
Rats
Sympathectomy, Chemical
Sympathetic Nervous System / physiology*
Grant Support
ID/Acronym/Agency:
NS 07687/NS/NINDS NIH HHS; NS 10928/NS/NINDS NIH HHS
Chemical
Reg. No./Substance:
55-65-2/Guanethidine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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