Document Detail

Influence of surgery on survival in 145 patients with left main coronary artery disease.
MedLine Citation:
PMID:  1098805     Owner:  NLM     Status:  MEDLINE    
A total of 145 patients with greater than 50% obstruction of the left main coronary artery (LMC) were studied by coronary arteriography. Of the 140 who survived cardiac catheterization, 121 were considered operable by coronary arteriography, and 19 were inoperable. Of the 121 operable patients, 32 were treated medically, and 89 had aortocoronary bypass surgery. Surgical mortality was 11%. The follow-up was from 1 to 72 months with a mean follow-up of 15 months. A survival table was plotted over a 24-month period. At 90 days survival in surgical patients was 85%, medical patients 72%, and inoperable patients 64%. At one year 82% of surgical patients were alive compared with 61% of medically treated operable patients (P less than 0.05). Thereafter, the survival rate remained stable up to 23 months. Survival in inoperable patients was 38% at one year. Improved surgical survival was associated with the presence of preoperative collateral vessels and a left ventricular stroke index greater than 18 g-m/m2. The study demonstrates that survival is improved significantly by surgery in LMC patients. Since mortality occurs early after coronary arteriography, surgery should be offered early to operable patients.
J V Talano; P J Scanlon; W R Meadows; M Kahn; R Pifarre; R M Gunnar
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article    
Journal Detail:
Title:  Circulation     Volume:  52     ISSN:  0009-7322     ISO Abbreviation:  Circulation     Publication Date:  1975 Aug 
Date Detail:
Created Date:  1975-12-04     Completed Date:  1975-12-04     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0147763     Medline TA:  Circulation     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  I105-11     Citation Subset:  AIM; IM    
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MeSH Terms
Angiocardiography / adverse effects
Clinical Trials as Topic
Collateral Circulation
Coronary Artery Bypass / mortality*
Coronary Disease / mortality*,  physiopathology
Heart Ventricles / physiopathology
Middle Aged

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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