Document Detail

Influence of sperm surface antibodies on spontaneous pregnancy rates.
MedLine Citation:
PMID:  9696234     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To determine the rates of spontaneous pregnancies among women whose infertile male partners had sperm surface antibodies. DESIGN: Retrospective analysis. SETTING: Infertility clinic of a university referral center. PATIENT(S): One hundred fifty-seven infertile couples; the male partner had IgA and/or IgG sperm surface antibody concentrations of >10%. INTERVENTION: None. MAIN OUTCOME MEASURE(S): Spontaneous pregnancy rates (PRs) over 6 years. RESULT(S): Spontaneous PRs correlated negatively with antibody concentrations. CONCLUSION(S): Although the chance of spontaneous pregnancy among women whose partners had sperm antibody concentrations of <50% was good, intracytoplasmic sperm injection should be recommended to patients with concentrations of >90%.
K Abshagen; H M Behre; T G Cooper; E Nieschlag
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Fertility and sterility     Volume:  70     ISSN:  0015-0282     ISO Abbreviation:  Fertil. Steril.     Publication Date:  1998 Aug 
Date Detail:
Created Date:  1998-08-27     Completed Date:  1998-08-27     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0372772     Medline TA:  Fertil Steril     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  355-6     Citation Subset:  IM    
Institute of Reproductive Medicine, University of Münster, Germany.
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MeSH Terms
Infertility, Male / immunology*
Pregnancy Rate
Receptors, Antigen, B-Cell / immunology*
Retrospective Studies
Spermatozoa / immunology*
Reg. No./Substance:
0/Receptors, Antigen, B-Cell

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