Document Detail

Influence of smoking on serum and milk of mothers, and their infants' serum insulin-like growth factor-I and insulin-like growth factor binding protein-3 levels.
MedLine Citation:
PMID:  15542930     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To investigate the serum and milk in active-smoking and nonsmoking mothers, and their infants' insulin-like growth factor-I (IGF-I) and insulin-like growth factor binding protein-3 (IGFBP-3) levels. DESIGN AND SETTING: A cohort study conducted at a tertiary medical center. Subjects: Forty-four mothers (age range: 21-34 years) and their newborns (7 days old) were enrolled in the study. Mothers were interviewed and classified according to their smoking status into one of two groups: the active-smoking mothers (n = 21) and the nonsmoking mothers (n = 23). RESULTS: There was no difference noted in either IGF-I, IGFBP-3 or IGF-I/IGFBP-3 ratios in serum and milk of mothers, and their infants' serum samples according to maternal smoking. CONCLUSION: This study demonstrated that maternal smoking (5-10 cigarettes/day) did not influence the maternal and infant serum levels of IGF-I and IGFBP-3 as well as the breast milk levels of these peptides.
Bahri Ermis; Konca Altinkaynak; Abdulkadir Yildirim; Behzat Ozkan
Publication Detail:
Type:  Journal Article     Date:  2004-11-09
Journal Detail:
Title:  Hormone research     Volume:  62     ISSN:  0301-0163     ISO Abbreviation:  Horm. Res.     Publication Date:  2004  
Date Detail:
Created Date:  2005-01-03     Completed Date:  2005-04-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0366126     Medline TA:  Horm Res     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  288-92     Citation Subset:  IM    
Division of Neonatology, Department of Pediatrics, School of Medicine, Zonguldak Karaelmas University, Kozlu, Zonguldak, Turkey.
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MeSH Terms
Infant, Newborn
Insulin-Like Growth Factor Binding Protein 3 / blood,  metabolism*
Insulin-Like Growth Factor I / metabolism*
Milk, Human / metabolism*
Smoking / physiopathology*
Reg. No./Substance:
0/Insulin-Like Growth Factor Binding Protein 3; 67763-96-6/Insulin-Like Growth Factor I

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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