| Influence of smoking on serum lipid and lipoprotein levels among family medicine patients. | |
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MedLine Citation:
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PMID: 19469266 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Smoking causes decrease of HDL-cholesterol (HDL-C) levels and increase of total cholesterol, triglyceride and LDL-cholesterol (LDL-C) levels. Low HDL-C levels and high cholesterol and LDL-C levels are associated with a higher risk for cardiovascular diseases. The aim of this study was to examine the effect of smoking status on serum lipid and lipoproteins levels among patients in family medicine practice. This trial was designed to detect differences in serum total cholesterol, triglyceride, LDL-C and HDL-C levels between smokers and non-smokers. We had placed a limit of 300 patients for data collection. We excluded 195 patients who met excluding criteria (diagnosis of diabetes mellitus, renal and hepatic failure, hypothyroidism; using beta blockers, thiazide diuretics, hormonal replacement therapy and corticosteroids; more than light physical activity; alcohol consumption and obesity), so the sample size included 105 randomly selected patients from Family Medicine Teaching Center Tuzla, mean age 52.05 +/- 11.61 years. Main outcomes were smoking status in all participants and serum total cholesterol, triglyceride, LDL-C and HDL-C levels in smokers and non-smokers. Our results showed that smoking prevalence was 49.52%. Smokers had significantly higher serum total cholesterol (P=0.01), triglyceride (P=0.002) and LDL-C level (P=0.03) and significantly lower HDL-C level (P=0.003) comparing with nonsmokers. There was no significant difference in serum lipid and lipoprotein levels between ex-smokers and never smokers. These results suggest that cigarette smoking adversely affects serum lipid and lipoprotein levels which further increases the risk for cardiovascular morbidity and mortality. |
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Authors:
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Olivera Batic-Mujanovic; Azijada Beganlic; Nizama Salihefendic; Nurka Pranjic; Zumreta Kusljugic |
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Publication Detail:
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Type: Journal Article; Randomized Controlled Trial |
Journal Detail:
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Title: Medicinski arhiv Volume: 62 ISSN: 0350-199X ISO Abbreviation: Med Arh Publication Date: 2008 |
Date Detail:
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Created Date: 2009-05-27 Completed Date: 2009-06-17 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0400722 Medline TA: Med Arh Country: Bosnia and Hercegovina |
Other Details:
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Languages: eng Pagination: 264-7 Citation Subset: IM |
Affiliation:
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Family Medicine Teaching Center, Health Center Tuzla. oliverabaticmujanovic@yahoo.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Female Humans Lipids / blood* Lipoproteins / blood* Male Middle Aged Smoking / blood* |
| Chemical | |
Reg. No./Substance:
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0/Lipids; 0/Lipoproteins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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