| Influence of smoking on maternal and neonatal serum malondialdehyde, superoxide dismutase, and glutathione peroxidase levels. | |
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MedLine Citation:
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PMID: 15648781 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This cohort study investigated postnatal serum malondialdehyde (MDA), superoxide dismutase (SOD), and glutathione peroxidase (GPx) levels in 14 active-smoking, 14 passive-smoking, and 15 non-smoking mothers and their newborns on day 7 post-partum. No significant differences were noted among the study groups with respect to MDA (p = 0.63) or SOD levels (p = 0.98) in either the mothers or their infants. However, there were significant differences among the study groups with respect to serum GPx activities in both the mothers (p = 0.028) and the infants (p = 0.039). When GPx activities were analyzed separately in both mothers and infants, a significant difference was noted only between the infants of smoking mothers and the infants of non-smoking mothers (p = 0.015). In conclusion, there was a significant increase in GPx activities of smoking mothers and their infants, suggesting that they may have been exposed to more oxidant stress. |
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Authors:
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Bahri Ermis; Rahmi Ors; Abdulkadir Yildirim; Ayhan Tastekin; Fatih Kardas; Fatih Akcay |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Annals of clinical and laboratory science Volume: 34 ISSN: 0091-7370 ISO Abbreviation: Ann. Clin. Lab. Sci. Publication Date: 2004 |
Date Detail:
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Created Date: 2005-01-14 Completed Date: 2005-04-28 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0410247 Medline TA: Ann Clin Lab Sci Country: United States |
Other Details:
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Languages: eng Pagination: 405-9 Citation Subset: IM |
Affiliation:
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Department of Pediatrics, School of Medicine, Zonguldak Karaelmas University, 67600 Kozlu/Zonguldak, Turkey. bahriermis@yahoo.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Cohort Studies Female Glutathione Peroxidase / blood* Humans Infant, Newborn / blood* Male Malondialdehyde / blood* Maternal-Fetal Exchange* Oxidative Stress / drug effects Pregnancy Prenatal Exposure Delayed Effects* Smoking / adverse effects, blood* Superoxide Dismutase / blood* Tobacco Smoke Pollution / adverse effects |
| Chemical | |
Reg. No./Substance:
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0/Tobacco Smoke Pollution; 542-78-9/Malondialdehyde; EC 1.11.1.9/Glutathione Peroxidase; EC 1.15.1.1/Superoxide Dismutase |
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