Document Detail

Influence of smoking on maternal and neonatal serum malondialdehyde, superoxide dismutase, and glutathione peroxidase levels.
MedLine Citation:
PMID:  15648781     Owner:  NLM     Status:  MEDLINE    
This cohort study investigated postnatal serum malondialdehyde (MDA), superoxide dismutase (SOD), and glutathione peroxidase (GPx) levels in 14 active-smoking, 14 passive-smoking, and 15 non-smoking mothers and their newborns on day 7 post-partum. No significant differences were noted among the study groups with respect to MDA (p = 0.63) or SOD levels (p = 0.98) in either the mothers or their infants. However, there were significant differences among the study groups with respect to serum GPx activities in both the mothers (p = 0.028) and the infants (p = 0.039). When GPx activities were analyzed separately in both mothers and infants, a significant difference was noted only between the infants of smoking mothers and the infants of non-smoking mothers (p = 0.015). In conclusion, there was a significant increase in GPx activities of smoking mothers and their infants, suggesting that they may have been exposed to more oxidant stress.
Bahri Ermis; Rahmi Ors; Abdulkadir Yildirim; Ayhan Tastekin; Fatih Kardas; Fatih Akcay
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Annals of clinical and laboratory science     Volume:  34     ISSN:  0091-7370     ISO Abbreviation:  Ann. Clin. Lab. Sci.     Publication Date:  2004  
Date Detail:
Created Date:  2005-01-14     Completed Date:  2005-04-28     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0410247     Medline TA:  Ann Clin Lab Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  405-9     Citation Subset:  IM    
Department of Pediatrics, School of Medicine, Zonguldak Karaelmas University, 67600 Kozlu/Zonguldak, Turkey.
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MeSH Terms
Cohort Studies
Glutathione Peroxidase / blood*
Infant, Newborn / blood*
Malondialdehyde / blood*
Maternal-Fetal Exchange*
Oxidative Stress / drug effects
Prenatal Exposure Delayed Effects*
Smoking / adverse effects,  blood*
Superoxide Dismutase / blood*
Tobacco Smoke Pollution / adverse effects
Reg. No./Substance:
0/Tobacco Smoke Pollution; 542-78-9/Malondialdehyde; EC Peroxidase; EC Dismutase

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