Document Detail

Influence of skin type, race, sex, and anatomic location on epidermal barrier function.
MedLine Citation:
PMID:  22507039     Owner:  NLM     Status:  In-Data-Review    
The intact skin represents a barrier to the uncontrolled loss of water, proteins, and plasma components from the organism. Owing to its complex structure, the epidermal barrier with its major layer, the stratum corneum, is the rate-limiting unit for the penetration of exogenous substances through the skin. The epidermal barrier is not a static structure. The status of different functions of the epidermis can be monitored by assessing specific biophysical parameters such as transepidermal water loss, stratum corneum hydration, and skin surface pH. Variables originating from the individual as well as exogenous factors have an important influence on the epidermal barrier parameters.
Razvigor Darlenski; Joachim W Fluhr
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinics in dermatology     Volume:  30     ISSN:  1879-1131     ISO Abbreviation:  Clin. Dermatol.     Publication Date:  2012 May 
Date Detail:
Created Date:  2012-04-17     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8406412     Medline TA:  Clin Dermatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  269-73     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Elsevier Inc. All rights reserved.
Department of Dermatology and Venereology, Tokuda Hospital-Sofia, 51B Nikola Vaptsarov Blvd, 1407 Sofia, Bulgaria.
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