Document Detail


Influence of saturated fat and linolenic acid on the association between intake of dairy products and blood pressure.
MedLine Citation:
PMID:  16801477     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Data on the association between dairy consumption and blood pressure have been inconsistent. We sought to examine the relation between dairy consumption and prevalent hypertension (HTN) among 4797 participants of the National Heart, Lung, and Blood Institute Family Heart Study. We used generalized estimating equations to estimate prevalence odds ratios of HTN across categories of dairy consumption. From the lowest to the highest sex-, age-, and energy-adjusted quartile of dairy consumption, there was an inverse association between dairy intake and prevalent HTN: odds ratios (95% CIs) were 1.0 (reference), 0.82 (0.64 to 1.05), 0.68 (0.53 to 0.89), and 0.62 (0.45 to 0.84), respectively, in a model adjusting for age, sex, energy intake, field center, body mass index, dietary linolenic acid, saturated and monounsaturated fat, sodium intake, potassium, caffeine, fiber, and fruits and vegetables (P for trend = 0.002). This association was independent of calcium intake and was mainly observed among subjects consuming fewer calories from saturated fat (P for interaction = 0.014). Dairy consumption was inversely associated with systolic (P for trend = 0.003) but not diastolic (P for trend = 0.09) blood pressure. Although subjects consuming > or = 2 servings per day of dairy products and higher total linolenic acid had the lowest prevalence odds of HTN, there was no evidence for interaction between linolenic acid and dairy consumption on HTN (P for interaction = 0.65). In conclusion, our data indicate an inverse association between dairy consumption and prevalent HTN that was independent of dietary calcium, mainly among individuals consuming less saturated fat. This suggests that consumption of low-fat dairy products might be more beneficial for preventing HTN.
Authors:
Luc Djoussé; James S Pankow; Steven C Hunt; Gerardo Heiss; Michael A Province; Edmond K Kabagambe; R Curtis Ellison
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural     Date:  2006-06-26
Journal Detail:
Title:  Hypertension     Volume:  48     ISSN:  1524-4563     ISO Abbreviation:  Hypertension     Publication Date:  2006 Aug 
Date Detail:
Created Date:  2006-07-21     Completed Date:  2006-09-05     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  7906255     Medline TA:  Hypertension     Country:  United States    
Other Details:
Languages:  eng     Pagination:  335-41     Citation Subset:  IM    
Affiliation:
Division of Aging, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02120, USA. ldjousse@rics.bwh.harvard.edu
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MeSH Terms
Descriptor/Qualifier:
Adult
Age Distribution
Aged
Aged, 80 and over
Blood Pressure* / drug effects
Calcium, Dietary
Cross-Sectional Studies
Dairy Products*
Diet*
Dietary Fats
Dietary Fats, Unsaturated
Fatty Acids*
Female
Humans
Hypertension / epidemiology*
Male
Middle Aged
Odds Ratio
Prevalence
Sex Distribution
United States
alpha-Linolenic Acid* / pharmacology
Grant Support
ID/Acronym/Agency:
5K01-HL70444/HL/NHLBI NIH HHS; U01 HL 67893/HL/NHLBI NIH HHS; U01 HL56563/HL/NHLBI NIH HHS; U01 HL56564/HL/NHLBI NIH HHS; U01 HL56565/HL/NHLBI NIH HHS; U01 HL56566/HL/NHLBI NIH HHS; U01 HL56567/HL/NHLBI NIH HHS; U01 HL56568/HL/NHLBI NIH HHS; U01 HL56569/HL/NHLBI NIH HHS; U01 HL67894/HL/NHLBI NIH HHS; U01 HL67895/HL/NHLBI NIH HHS; U01 HL67896/HL/NHLBI NIH HHS; U01 HL67897/HL/NHLBI NIH HHS; U01 HL67898/HL/NHLBI NIH HHS; U01 HL67899/HL/NHLBI NIH HHS; U01 HL67900/HL/NHLBI NIH HHS; U01 HL67901/HL/NHLBI NIH HHS; U01 HL67902/HL/NHLBI NIH HHS
Chemical
Reg. No./Substance:
0/Calcium, Dietary; 0/Dietary Fats; 0/Dietary Fats, Unsaturated; 0/Fatty Acids; 463-40-1/alpha-Linolenic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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