Document Detail


Influence of red chilli on lipids and bile acids in different tissues in experimental colon cancer.
MedLine Citation:
PMID:  7896308     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Effect of feeding red chilli on the levels of lipids, fecal bile acids and fecal sterols was studied in animals given 1,2-dimethylhydrazine (DMH). When the three experimental groups were compared with control, the levels of cholesterol increased while phospholipids and free fatty acids decreased or showed no alteration in most of the tissues studied. Cholesterol-phospholipid ratio was high in both DMH as well as in the chilli + DMH treated groups. Weekly assessment of bile acids and neutral sterols showed a significant increase in all the three experimental groups, when compared to the control rats. Morphological and histopathological studies show that there were a number of visible malignant tumors in the colon and intestine of all the three experimental animals.
Authors:
S Chitra; K Sabitha; N Nalini; V P Menon
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Indian journal of experimental biology     Volume:  32     ISSN:  0019-5189     ISO Abbreviation:  Indian J. Exp. Biol.     Publication Date:  1994 Nov 
Date Detail:
Created Date:  1995-04-25     Completed Date:  1995-04-25     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0233411     Medline TA:  Indian J Exp Biol     Country:  INDIA    
Other Details:
Languages:  eng     Pagination:  793-6     Citation Subset:  IM    
Affiliation:
Department of Biochemistry, Annamalai University, India.
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MeSH Terms
Descriptor/Qualifier:
Animals
Bile Acids and Salts / metabolism*
Colonic Neoplasms / chemically induced,  metabolism*
Intestines / metabolism*
Lipid Metabolism*
Liver / metabolism*
Male
Rats
Rats, Sprague-Dawley
Spices*
Chemical
Reg. No./Substance:
0/Bile Acids and Salts

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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