Document Detail


Influence of protein calorie malnutrition and fasting on the activities of delta-aminolevulinic acid dehydratase and porphobilinogen deaminase in rats.
MedLine Citation:
PMID:  8000239     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Rats were fed a restricted standard diet (6-8 g daily) for 4 weeks. The erythrocyte activity of delta-aminolevulinic acid dehydratase showed a very expressed decrease (7.9 times) and its hepatic activity diminished more than twice. Porphobilinogen deaminase activity was reduced by 40% and 17% respectively. After a 3-day total food deprivation delta-aminolevulinic acid dehydratase activity remained unchanged in red blood cells, but an increase by 52% was found in the liver. The erythrocyte activity of porphobilinogen deaminase was reduced by 42% and its hepatic activity--by 16%.
Authors:
D G Adjarov; E N Naydenova; M A Kerimova; K D Pentieva; L B Ivanova; A V Ivanova
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie     Volume:  46     ISSN:  0940-2993     ISO Abbreviation:  Exp. Toxicol. Pathol.     Publication Date:  1994 Aug 
Date Detail:
Created Date:  1995-01-26     Completed Date:  1995-01-26     Revised Date:  2006-10-30    
Medline Journal Info:
Nlm Unique ID:  9208920     Medline TA:  Exp Toxicol Pathol     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  199-202     Citation Subset:  IM    
Affiliation:
Centre of Hygiene, Ecology and Nutrition, Sofia, Bulgaria.
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MeSH Terms
Descriptor/Qualifier:
Animals
Erythrocytes / enzymology
Fasting / metabolism*
Female
Hydroxymethylbilane Synthase / blood,  metabolism*
Liver / enzymology
Porphobilinogen Synthase / blood,  metabolism*
Protein-Energy Malnutrition / enzymology*
Rats
Rats, Wistar
Chemical
Reg. No./Substance:
EC 2.5.1.61/Hydroxymethylbilane Synthase; EC 4.2.1.24/Porphobilinogen Synthase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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