Document Detail

Influence of progesterone on arterial blood and CSF acid-base balance in women.
MedLine Citation:
PMID:  6797997     Owner:  NLM     Status:  MEDLINE    
To study the mechanism of the action of progesterone on pulmonary ventilation during pregnancy, arterial and cerebrospinal fluid (CSF) acid-base parameters were measured in 59 pregnant and 36 nonpregnant women at the periods of follicular phase, luteal phase, early pregnancy, late pregnancy, and puerperium. Marked respiratory alkalosis in both arterial blood and CSF was observed in pregnancy and puerperium. The degree of hypocapnia observed in the luteal phase and during pregnancy was closely related to the progesterone level in arterial blood. In conclusion, it is unlikely that the observed hyperventilation results from stimulation at the central chemosensitive areas or peripheral chemoreceptors.
H Machida
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of applied physiology: respiratory, environmental and exercise physiology     Volume:  51     ISSN:  0161-7567     ISO Abbreviation:  J Appl Physiol Respir Environ Exerc Physiol     Publication Date:  1981 Dec 
Date Detail:
Created Date:  1982-03-22     Completed Date:  1982-03-22     Revised Date:  2013-09-26    
Medline Journal Info:
Nlm Unique ID:  7801242     Medline TA:  J Appl Physiol Respir Environ Exerc Physiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1433-6     Citation Subset:  IM    
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MeSH Terms
Acid-Base Equilibrium*
Carbon Dioxide / metabolism
Cerebrospinal Fluid / metabolism
Electrolytes / blood
Lactates / metabolism
Lactic Acid
Oxygen Consumption
Progesterone / blood,  cerebrospinal fluid,  physiology*
Reg. No./Substance:
0/Electrolytes; 0/Lactates; 124-38-9/Carbon Dioxide; 50-21-5/Lactic Acid; 57-83-0/Progesterone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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