Document Detail

Influence of primary generalised osteoarthritis on development of secondary osteoarthritis.
MedLine Citation:
PMID:  6134929     Owner:  NLM     Status:  MEDLINE    
The hands and knees of 150 patients who had undergone unilateral meniscectomy 19 or more (mean 24 . 7) years before were examined for evidence of osteoarthritis (OA). 65 had X-ray changes in the hands consistent with primary generalised OA. These patients showed more frequent and more severe knee OA, judged clinically and radiologically, in both unoperated and operated knees, than did the 85 patients without hand OA. The increased frequency in operated knees was independent of sex and age variables between the groups and remained significant after exclusion of patients with OA on the unoperated side. This study demonstrated that predisposition to "primary" OA influences the development and severity of "secondary" OA. It invalidates clear distinction between these subsets and emphasises the multifactorial nature of the disease.
M Doherty; I Watt; P Dieppe
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Lancet     Volume:  2     ISSN:  0140-6736     ISO Abbreviation:  Lancet     Publication Date:  1983 Jul 
Date Detail:
Created Date:  1983-08-11     Completed Date:  1983-08-11     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  2985213R     Medline TA:  Lancet     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  8-11     Citation Subset:  AIM; IM    
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MeSH Terms
Hand / radiography
Knee Joint* / radiography,  surgery
Middle Aged
Osteoarthritis / etiology*,  radiography
Postoperative Complications / radiography
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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