Document Detail


Influence of pressure on the retention of sugars in hydrophilic interaction chromatography.
MedLine Citation:
PMID:  20041449     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
Pressure can influence the retention of analytes in hydrophilic interaction chromatography as well as in RP chromatography. We demonstrate that the retention of sugars in hydrophilic interaction chromatography decreases with pressure, and interpret the observation as a gain in solvation, or more specifically hydration, as the sugar molecules enter the water-rich stationary phase.
Authors:
Uwe D Neue; Chris J Hudalla; Pamela C Iraneta
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of separation science     Volume:  33     ISSN:  1615-9314     ISO Abbreviation:  J Sep Sci     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-06-21     Completed Date:  2010-09-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101088554     Medline TA:  J Sep Sci     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  838-40     Citation Subset:  -    
Affiliation:
Waters Corporation, Milford, MA 01721, USA. Uwe_Neue@Waters.com
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