Document Detail

Influence of precursors and inhibitor on the production of extracellular 5-aminolevulinic acid and biomass by Rhodopseudomonas palustris KG31.
MedLine Citation:
PMID:  19420716     Owner:  NLM     Status:  MEDLINE    
5-Aminolevulinic acid (ALA) and the biomass of photosynthetic bacteria, Rhodopseudomonas palustris KG31, have very high potential for development and exploitation as bioherbicide and biofertilizer respectively. In this work, the effects of two precursors and an inhibitor of aminolevulinic dehydratase (ALAD) added to the VFA culture medium on the production of ALA and biomass were investigated. The experimental runs were carried out according to a Box-Behnken design. The precursors were added to the medium at the beginning of cultivation, while the inhibitor was added after 24 h. Statistical analysis indicated that levulinic acid (LA) has a positive effect on ALA production while glycine has a negative effect on biomass production. In order to enhance both ALA and biomass products, the most suitable medium was VFA medium supplemented with 3.0 mM glycine and 10 mM LA, giving ALA and biomass of 182.91 microM and 3.1 gDCW/l within 54 h.
Angkana Saikeur; Wanna Choorit; Poonsuk Prasertsan; Duangporn Kantachote; Ken Sasaki
Related Documents :
1468986 - Isolation and identification of 3-propylidene-delta 1-pyrroline-5-carboxylic acid, a bi...
11982386 - Conformation-dependent reaction thermochemistry: study of lactones and lactone enolates...
14577666 - Synthesis of fluorinated analogs of myristic acid as potential inhibitors of egyptian a...
2628306 - Synergistic effect of allyl isopropyl acetamide with cadmium on hepatic heme synthesis ...
16346916 - Partial chemical and physical characterization of two extracellular polysaccharides pro...
8881596 - Polyunsaturated fatty acids status in blood, heart, liver, intestine, retina and brain ...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2009-05-07
Journal Detail:
Title:  Bioscience, biotechnology, and biochemistry     Volume:  73     ISSN:  1347-6947     ISO Abbreviation:  Biosci. Biotechnol. Biochem.     Publication Date:  2009 May 
Date Detail:
Created Date:  2009-05-25     Completed Date:  2009-08-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9205717     Medline TA:  Biosci Biotechnol Biochem     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  987-92     Citation Subset:  IM    
School of Agricultural Technology, Walailak University, Nakhon Si Thammarat, Thailand.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Aminolevulinic Acid / metabolism*
Enzyme Inhibitors / pharmacology
Extracellular Space / drug effects*,  metabolism*
Glycine / pharmacology
Levulinic Acids / pharmacology
Models, Biological
Porphobilinogen Synthase / antagonists & inhibitors
Rhodopseudomonas / drug effects*,  metabolism*
Succinic Acid / pharmacology
Reg. No./Substance:
0/Enzyme Inhibitors; 0/Levulinic Acids; 106-60-5/Aminolevulinic Acid; 110-15-6/Succinic Acid; 123-76-2/levulinic acid; 56-40-6/Glycine; EC Synthase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Inhibitory effect of Poncirus trifoliate on acetylcholinesterase and attenuating activity against tr...
Next Document:  Enzymatic properties of futalosine hydrolase, an enzyme essential to a newly identified menaquinone ...