Document Detail

Influence of posture on left ventricular long- and short-axis shortening.
MedLine Citation:
PMID:  12234779     Owner:  NLM     Status:  MEDLINE    
End-diastolic volume and left ventricular stroke volume are increased in the supine compared with upright position, but the contribution of long-axis (LAS) and short-axis shortening (SAS) to these changes with change in posture has not been established. We examined long- and short-axis motion and dimensions with echocardiography in 10 healthy subjects in the upright and supine position. Long-axis length at end diastole was almost identical, whereas the diastolic short-axis diameter was increased in the supine position. At end systole, there was a decreased long-axis length and increased short-axis length in the supine vs. upright position. Both LAS and SAS were enhanced in supine vs. upright positions [LAS: 9.3 +/- 2.2 vs. 15.1 +/- 3.1 mm (P < 0.001); SAS: 12.7 +/- 3.2 vs. 16.3 +/- 2.8 mm (P < 0.001)], presumably via Starling mechanisms. LAS increased more in the lateral part of the mitral annulus than in the septal part [7.7 +/- 2.6 vs. 4.0 +/- 2.8 mm (P < 0.006)], which implies that the more spherical form, in the supine position, induces more stretch at the lateral free wall than in the ventricular septum. These findings support the notion that Starling mechanisms affect systolic LAS.
Patrik Sundblad; Bengt Wranne
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2002-06-13
Journal Detail:
Title:  American journal of physiology. Heart and circulatory physiology     Volume:  283     ISSN:  0363-6135     ISO Abbreviation:  Am. J. Physiol. Heart Circ. Physiol.     Publication Date:  2002 Oct 
Date Detail:
Created Date:  2002-09-17     Completed Date:  2002-10-17     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  100901228     Medline TA:  Am J Physiol Heart Circ Physiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  H1302-6     Citation Subset:  IM; S    
Section of Environmental Physiology, Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm S-171 77, Sweden.
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MeSH Terms
Diastole / physiology
Heart / physiology*
Posture / physiology*
Stroke Volume / physiology*
Supine Position / physiology
Systole / physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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