Document Detail

Influence of posture on gas exchange in artificially ventilated patients with focal lung disease.
MedLine Citation:
PMID:  6406579     Owner:  NLM     Status:  MEDLINE    
Six patients were artificially ventilated for a focal lung disease localized to one lung in four cases and to both lower lobes in two. Despite an inspired oxygen concentration of 100% the mean PaO2 was 115 mmHg. The addition of PEEP slightly improved PaO2 in two patients but led to deterioration in four. We therefore studied the effects of posture. Patients with unilateral disease were placed in the lateral position with the healthy lung dependent. The two patients with both lower lobes involved were tilted into the Trendelenburg position. The mean PaO2 rose from 98.4 to 199.5 mmHg. Posture was maintained as long as a beneficial effect was demonstrable. The disappearance of this effect was associated either with recovery (three patients) or with the extension of the pneumonia (three patients). The improvement of gas exchange can be accounted for by the rearrangement of ventilation/perfusion relationships. This management could avoid the need for differential lung ventilation.
P Prokocimer; J Garbino; M Wolff; B Regnier
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Intensive care medicine     Volume:  9     ISSN:  0342-4642     ISO Abbreviation:  Intensive Care Med     Publication Date:  1983  
Date Detail:
Created Date:  1983-07-29     Completed Date:  1983-07-29     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7704851     Medline TA:  Intensive Care Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  69-72     Citation Subset:  IM    
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MeSH Terms
Carbon Dioxide / blood
Lung Diseases / blood,  therapy*
Middle Aged
Oxygen / blood
Positive-Pressure Respiration / methods*
Reg. No./Substance:
124-38-9/Carbon Dioxide; 7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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