| Influence of physical exercise and gender on acetylcholinesterase and butyrylcholinesterase activity in human blood samples. | |
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MedLine Citation:
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PMID: 22149082 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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The determination of cholinesterase activity in plasma and erythrocytes serves as a useful and sensitive biomarker of exposure to organophosphorus and carbamate pesticides. However, acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) activity may be influenced by factors such as age, gender, drugs, and physical exercise. The aim of this study was to evaluate the effects of gender and physical exercise on the activity of AChE and BuChE in healthy individuals. The values for both enzymes were lower for women. Physical exercise increased the levels of BuChE, and had no significant effect on AChE. To our knowledge, this is the first clinical study evaluating the influence of physical exercise in levels of these enzymes. Considering that cholinesterase activity is a useful parameter in assessing the exposure of individuals to pesticides, it is important to understand factors that influence the determination of the enzymes in order to avoid the erroneous interpretation of results. |
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Authors:
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Karine Rigon Zimmer; Claiton Leonetti Lencina; Aline Rigon Zimmer; Flávia Vallãdao Thiesen |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-12-9 |
Journal Detail:
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Title: International journal of environmental health research Volume: - ISSN: 1369-1619 ISO Abbreviation: - Publication Date: 2011 Dec |
Date Detail:
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Created Date: 2011-12-13 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9106628 Medline TA: Int J Environ Health Res Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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a Faculdade de Farmácia , Instituto de Toxicologia, Pontíficia Universidade Católica do Rio Grande do Sul , Av Ipiranga 6681, Prédio 12 D, Porto Alegre 90630-180, Rio Grande do Sul , Brazil. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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