Document Detail

Influence of patient-related and surgery-related risk factors on cognitive performance, emotional state, and convalescence after cardiac surgery.
MedLine Citation:
PMID:  17765645     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Cardiac surgery may account for complications such as cognitive impairment, depression, and delay of convalescence. This study investigated the influence of different risk factors on cognitive performance, emotional state, and convalescence. METHODS: We included 83 patients undergoing cardiac surgery who had no indication of postoperative delirium. Psychometric testing was performed 1 day before and 7 days after surgery. Neuron-specific enolase (NSE) levels were measured 1 day before and 36 h after surgery. RESULTS: Depression score increased after surgery, but patients showed no clinically significant depression. Postoperative cognitive performance correlated with postoperative depression level and preoperative cognitive performance. Forty-three percent of patients showed postoperative decline. Older patients exhibited a higher postoperative increase in NSE concentrations. Patients undergoing coronary artery bypass grafts or combined procedures exhibited more medical risk factors than those undergoing valve surgery alone. The number of bypass grafts was associated with time of hospitalization, and the number of patient-related risk factors correlated with stay in intensive care unit. CONCLUSIONS: For elderly patients undergoing cardiac surgery, older age, total preexisting medical risk factors, and surgery duration seem to be the most important factors influencing cognitive outcome and convalescence. Results show that, also for patients without postoperative delirium, medical risk factors and intraoperative parameters can result in delay of convalescence.
Rottraut Ille; Theresa Lahousen; Stefan Schweiger; Peter Hofmann; Hans-Peter Kapfhammer
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cardiovascular revascularization medicine : including molecular interventions     Volume:  8     ISSN:  1553-8389     ISO Abbreviation:  -     Publication Date:    2007 Jul-Sep
Date Detail:
Created Date:  2007-09-03     Completed Date:  2007-11-01     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101238551     Medline TA:  Cardiovasc Revasc Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  166-9     Citation Subset:  IM    
University Hospital of Psychiatry, Graz, Austria.
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MeSH Terms
Age Factors
Cognition Disorders / etiology*
Convalescence* / psychology
Coronary Artery Bypass / adverse effects*,  psychology
Depression / etiology*
Heart Valve Prosthesis Implantation / adverse effects*,  psychology
Length of Stay
Middle Aged
Phosphopyruvate Hydratase / blood
Risk Assessment
Risk Factors
Time Factors
Treatment Outcome
Reg. No./Substance:
EC Hydratase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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