Document Detail


Influence of parity on first trimester endovascular trophoblast invasion.
MedLine Citation:
PMID:  16580391     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To assess the effect of parity on endovascular trophoblastic invasion in early pregnancy. DESIGN: Observational study. SETTING: Teaching hospital. PATIENT(S): Healthy women at 10-14 weeks of gestation. INTERVENTION(S): Surgical termination of pregnancy for nonmedical reasons. MAIN OUTCOME MEASURE(S): Products of conception were blindly examined histologically with regard to the extent of decidual endovascular trophoblast invasion. RESULT(S): Samples were obtained from 20 nulliparous and 10 parous women. The presence of normal intradecidual endovascular trophoblast invasion was identified with a similar frequency in both groups (P=.28). However, the proportion of decidual vessels with endovascular trophoblast invasion was significantly higher in parous women (60%) compared with nulliparous women (32%, P<.001). CONCLUSION(S): Endovascular trophoblast invasion in early pregnancy is more extensive in parous women who already had an uncomplicated pregnancy than in nulliparous women.
Authors:
Federico Prefumo; Ramesh Ganapathy; Basky Thilaganathan; Neil J Sebire
Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2006-03-09
Journal Detail:
Title:  Fertility and sterility     Volume:  85     ISSN:  1556-5653     ISO Abbreviation:  Fertil. Steril.     Publication Date:  2006 Apr 
Date Detail:
Created Date:  2006-04-03     Completed Date:  2006-05-11     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0372772     Medline TA:  Fertil Steril     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1032-6     Citation Subset:  IM    
Affiliation:
Division of Obstetrics and Gynaecology, St. George's, University of London, London, United Kingdom. fprefumo@sgul.ac.uk
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Embryo Implantation / physiology
Endothelium, Vascular / physiology*
Female
Humans
Parity / physiology*
Pregnancy
Pregnancy Trimester, First / physiology*
Trophoblasts / physiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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