Document Detail

Influence of ouabain of electrolyte and water transport in the rabbit ileum and colon in vitro and in vivo.
MedLine Citation:
PMID:  1787845     Owner:  NLM     Status:  MEDLINE    
We studied the influence of the Na(+)-K+ pump inhibitor ouabain on water and electrolyte transport in the rabbit distal ileum and proximal colon in vitro and in vivo. Under in vitro conditions, ouabain markedly reduced the absorption of water, sodium, chloride and bicarbonate, and reduced potassium secretion in both the ileum and the colon. In vivo results were similar but less marked than those obtained in vitro, with significant differences only at the level of the distal ileum.
M C Galindo; M S Campos; J A Garcia; F Lisbona
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Die Nahrung     Volume:  35     ISSN:  0027-769X     ISO Abbreviation:  Nahrung     Publication Date:  1991  
Date Detail:
Created Date:  1992-03-23     Completed Date:  1992-03-23     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0142530     Medline TA:  Nahrung     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  577-80     Citation Subset:  IM    
Department of Physiology, Faculty of Pharmacy, University of Granada, Spain.
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MeSH Terms
Bicarbonates / metabolism
Biological Transport / drug effects
Body Water / metabolism*
Chlorides / metabolism
Colon / drug effects,  metabolism*
Electrolytes / metabolism*
Ileum / drug effects,  metabolism*
Ouabain / pharmacology*
Potassium / metabolism
Sodium / metabolism
Reg. No./Substance:
0/Bicarbonates; 0/Chlorides; 0/Electrolytes; 630-60-4/Ouabain; 7440-09-7/Potassium; 7440-23-5/Sodium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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