Document Detail


Influence of oleic acid on serum lipoprotein-X in vitro.
MedLine Citation:
PMID:  923079     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Lipoprotein-X is no longer detectable in serum by either the agar gel-electrophoresis/polyanion precipitation technique or immunoelectrophoresis with specific antiserum after in vitro addition of oleic acid. Evidence is presented which indicates that this ostensible loss is due not to its destruction, but rather to altered electrophoretic mobility. The findings suggest an explanation for the well known post-heparin "disappearance" of lipoprotein-X, and indicate that caution may be needed in the interpretation of such lipoprotein-X testing of sera from subjects with increased concentrations of lysolipids in their blood.
Authors:
T J Muckle; J A Edwards; P Auckland
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Clinical chemistry     Volume:  23     ISSN:  0009-9147     ISO Abbreviation:  Clin. Chem.     Publication Date:  1977 Dec 
Date Detail:
Created Date:  1978-01-27     Completed Date:  1978-01-27     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9421549     Medline TA:  Clin Chem     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  2302-5     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Cholestasis / blood
Electrophoresis, Agar Gel / methods
Humans
Immunoelectrophoresis / methods
Lipoproteins / blood*
Oleic Acids*
Chemical
Reg. No./Substance:
0/Lipoproteins; 0/Oleic Acids

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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