| Influence of moderate hypoxia on tolerance to high-intensity exercise. | |
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MedLine Citation:
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PMID: 21556815 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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It remains uncertain as how the reduction in systemic oxygen transport limits high-intensity exercise tolerance. 11 participants (5 males; age 35 ± 10 years; peak [Formula: see text] 3.5 ± 0.4 L min(-1)) performed cycle ergometry to the limit of tolerance: (1) a ramp test to determine ventilatory threshold (VT) and peak [Formula: see text]; (2) three to four constant-load tests in order to model the linear P-t (-1) relationship for estimation of intercept (critical power; CP) and slope (AWC). All tests were performed in a random order under moderate hypoxia (FiO(2) = 0.15) and normoxia. The linearity of the P-t (-1) relationship was retained under hypoxia, with a systematic reduction in CP (220 ± 25 W vs. 190 ± 28 W; P < 0.01) but no significant difference in AWC (11.7 ± 5.5 kJ vs. 12.1 ± 4.4 kJ; P > 0.05). However, large individual variations in the change of the latter were observed (-36 to +66%). A significant relationship was found between the % change in CP (r = 0.80, P < 0.01) and both peak [Formula: see text] (CP: r = -0.65, P < 0.05) and VT values recorded under normoxia (CP: r = -0.65, P < 0.05). The present study demonstrates the aerobic nature of the intercept of the P-t (-1) relationship, i.e. CP. However, the extreme within-individual changes in AWC do not support the original assumption that AWC reflects a finite energy store. Lower hypoxia-induced decrements in CP were observed in aerobically fitter participants. This study also demonstrates the greater ability these participants have to exercise at supra-CP but close to CP workloads under moderate hypoxia. |
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Authors:
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J Dekerle; P Mucci; H Carter |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-5-10 |
Journal Detail:
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Title: European journal of applied physiology Volume: - ISSN: 1439-6327 ISO Abbreviation: - Publication Date: 2011 May |
Date Detail:
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Created Date: 2011-5-10 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100954790 Medline TA: Eur J Appl Physiol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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EA Physical Activity, Muscle, Health, University of Lille-North of France, Ronchin, France, j.dekerle@bton.ac.uk. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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