Document Detail


Influence of moderate altitude on blood lactate and heart rate in a standardized exercise test in healthy volunteers.
MedLine Citation:
PMID:  16268051     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Nineteen healthy volunteers were exposed to a standardized exercise test at sea level (SLa), at an altitude of 1700 m before (1700a) and after a moderate 10-day mountain training (1700b), with a final control four weeks later at sea level (SLb). Vital signs, blood lactate and arterial oxygen saturation were determined prior, during or after the exercise test. Whereas systolic blood pressure and heart rate at rest did not change substantially, diastolic blood pressure decreased at the final control (SLb, p<0.05) and oxygen saturation was significantly lower at 1700 m (1700a, 1700b, p<0.01). Lactate at rest increased from 1.16 (SLa) to 1.97 (1700a) mmol/l after acute exposure followed by a slight reduction after adaptation (p<0.05). The mean maximum lactate levels were as follows: 6.03, 10.56, 6.22 and 8.75 (p<0.01). The mean maximum performance increased during the study (225.6, 223.3, 231.6, 248.1 Watt, p<0.01). Lactate versus workload curves did not show a marked shift to the right. No significant changes of maximum heart rates during the exercise test were found. In conclusion, a sojourn at 1700 m provokes an increase of lactate levels with subsequent reduction after acclimatization and has a significant positive impact on the mean maximum performance after moderate mountain training.
Authors:
H J Koch; C Raschka
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta physiologica Hungarica     Volume:  92     ISSN:  0231-424X     ISO Abbreviation:  Acta Physiol Hung     Publication Date:  2005  
Date Detail:
Created Date:  2005-11-04     Completed Date:  2005-11-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8309201     Medline TA:  Acta Physiol Hung     Country:  Hungary    
Other Details:
Languages:  eng     Pagination:  139-46     Citation Subset:  IM    
Affiliation:
Netrologische Universitätsklinik am Bezirksklinikum Regensburg, Deutschland. horst.koch@medbo.de
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MeSH Terms
Descriptor/Qualifier:
Acclimatization / physiology*
Adult
Altitude*
Blood Pressure / physiology
Exercise Test / methods*
Female
Heart Rate / physiology*
Humans
Lactic Acid / blood*
Male
Chemical
Reg. No./Substance:
50-21-5/Lactic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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