Document Detail

Influence of minimal angiographic visible collateral circulation on myocardial function during PTCA.
MedLine Citation:
PMID:  1742905     Owner:  NLM     Status:  MEDLINE    
The potential protective role of angiographically visible minimal collateral circulation in diagnostic angiograms, not reaching or filling the target vessel (RENTROP class 1), on myocardial function during percutaneous transluminal coronary angioplasty (PTCA), was studied in two groups of patients undergoing elective PTCA of the left anterior descending artery (LAD). In the first study group consisting of 22 patients, influence of collateral circulation class 1 on left ventricular regional function was evaluated. In this group, 14 patients showed no angiographic collaterals and 8 patients showed collateral circulation class 1 in diagnostic angiograms. Increase of end-diastolic and end-systolic volume indices as well as decrease of global left ventricular function was not significantly different inpatients with and without such minimal collateral circulation. In patients without collaterals, the decrease of regional left ventricular function was significantly more pronounced in the left anterior length segment (p less than 0.05) and a trend was observed in the anterolateral (p = 0.059) and apical (p = 0.053) segments. In a second group, consisting of 29 patients, hemodynamic parameters were measured and, in addition to grading of collateral circulation in diagnostic angiograms, angiographically visible collateral circulation was estimated during occlusion of the LAD by injecting contrast materials into the right coronary artery. An increase of angiographically visible collaterals during the ischemic period of various degrees was documented in 26 (90%) of 29 patients. Combining patients of both study groups, increase in left ventricular end-diastolic pressure during ischemia was significantly higher (p less than 0.05) in patients without collaterals on diagnostic angiography (n = 34) than in patients with collateral circulation class 1 (n = 14).(ABSTRACT TRUNCATED AT 250 WORDS)
M Dittel; H Prachar; W Enenkel
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical cardiology     Volume:  14     ISSN:  0160-9289     ISO Abbreviation:  Clin Cardiol     Publication Date:  1991 Sep 
Date Detail:
Created Date:  1992-01-14     Completed Date:  1992-01-14     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7903272     Medline TA:  Clin Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  713-9     Citation Subset:  IM    
Medical Department of Cardiology, Krankenhaus Lainz, Vienna, Austria.
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MeSH Terms
Angina Pectoris / radiography*,  therapy*
Angioplasty, Transluminal, Percutaneous Coronary*
Collateral Circulation / physiology*
Coronary Angiography
Coronary Circulation / physiology*
Coronary Disease / radiography*,  therapy*
Hemodynamics / physiology
Middle Aged
Myocardial Contraction / physiology
Prospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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