Document Detail


[Influence of methylcobalamin and cyanocobalamin on the neoplastic process in rats]
MedLine Citation:
PMID:  199903     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The effect of methylcobalamine (5.6-dimethylbenzimidazolyl-Co-methylcobamide, CH3-B12) and cyanocobalamine (5,6-dimethylbenzimidazolyly-Co-cyanocobamide, CN-B12) on the growth of Walker's carcinosarcoma and longevity of white noninbred rats with implanted Zajdela ascites hepatoma was studied. The two agents exerted a similar effect. They 1) reduced the survival of rats with implanted Zajdela ascites hepatoma and Walker's carcinosarcoma; 2) did not increase the cell concentration in ascites; and 3) increased the total volume of ascites.
Authors:
V R Kal'nev; Iu A Rachkus; S I Kanopkaĭte
Related Documents :
15456273 - Structure-activity relationship of heterobase-modified 2'-c-methyl ribonucleosides as i...
17119333 - An experimental study of tympanic membrane and manubrium vibrations in rats.
1532703 - Comparative effects of chronic ethanol consumption on the properties of mitochondria fr...
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Prikladnaia biokhimiia i mikrobiologiia     Volume:  13     ISSN:  0555-1099     ISO Abbreviation:  Prikl. Biokhim. Mikrobiol.     Publication Date:    1977 Sep-Oct
Date Detail:
Created Date:  1977-12-29     Completed Date:  1977-12-29     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0023416     Medline TA:  Prikl Biokhim Mikrobiol     Country:  USSR    
Other Details:
Languages:  eng     Pagination:  677-81     Citation Subset:  IM    
Vernacular Title:
Vliiani metilkobalamina i tsiankobalamina na protsess neoplazii u krys.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Carcinogens*
Carcinoma 256, Walker / chemically induced*
Carcinoma, Hepatocellular / chemically induced*
Liver Neoplasms / chemically induced*
Male
Neoplasm Transplantation
Neoplasms, Experimental
Rats
Vitamin B 12 / toxicity*
Chemical
Reg. No./Substance:
0/Carcinogens; 68-19-9/Vitamin B 12

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  A modified method for the preparation of agarose.
Next Document:  Mechanisms of amitriptyline induced hypothermia in the rat.